9129767 76CNVERS 1 apa 50 date desc year Arcila, D. 18 https://dkarcila.scrippsprofiles.ucsd.edu/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22W2IRA9RD%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Santaquiteria%20et%20al.%22%2C%22parsedDate%22%3A%222025-01-17%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESantaquiteria%2C%20A.%2C%20Miller%2C%20E.%20C.%2C%20Rosas-Puchuri%2C%20U.%2C%20Pedraza-Marr%26%23xF3%3Bn%2C%20C.%20D.%20R.%2C%20Troyer%2C%20E.%20M.%2C%20Westneat%2C%20M.%20W.%2C%20Carnevale%2C%20G.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20%26amp%3B%20Betancur-R.%2C%20R.%20%282025%29.%20Colonization%20Dynamics%20Explain%20the%20Decoupling%20of%20Species%20Richness%20and%20Morphological%20Disparity%20in%20Syngnatharian%20Fishes%20across%20Oceans.%20%3Ci%3EThe%20American%20Naturalist%3C%5C%2Fi%3E%2C%20E000%26%23x2013%3BE000.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1086%5C%2F733931%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1086%5C%2F733931%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Colonization%20Dynamics%20Explain%20the%20Decoupling%20of%20Species%20Richness%20and%20Morphological%20Disparity%20in%20Syngnatharian%20Fishes%20across%20Oceans%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Aintzane%22%2C%22lastName%22%3A%22Santaquiteria%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elizabeth%20Christina%22%2C%22lastName%22%3A%22Miller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulises%22%2C%22lastName%22%3A%22Rosas-Puchuri%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carmen%20Del%20R.%22%2C%22lastName%22%3A%22Pedraza-Marr%5Cu00f3n%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Emily%20M.%22%2C%22lastName%22%3A%22Troyer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mark%20W.%22%2C%22lastName%22%3A%22Westneat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Giorgio%22%2C%22lastName%22%3A%22Carnevale%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dahiana%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricardo%22%2C%22lastName%22%3A%22Betancur-R.%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222025-01-17%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1086%5C%2F733931%22%2C%22ISSN%22%3A%220003-0147%2C%201537-5323%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.journals.uchicago.edu%5C%2Fdoi%5C%2F10.1086%5C%2F733931%22%2C%22collections%22%3A%5B%22F2MEDY88%22%2C%22BTBUS4GS%22%2C%2276CNVERS%22%5D%2C%22dateModified%22%3A%222025-02-12T16%3A53%3A23Z%22%7D%7D%2C%7B%22key%22%3A%22B8FA9BT9%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Miller%20et%20al.%22%2C%22parsedDate%22%3A%222024-11-27%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EMiller%2C%20E.%20C.%2C%20Faucher%2C%20R.%2C%20Hart%2C%20P.%20B.%2C%20Rinc%26%23xF3%3Bn-Sandoval%2C%20M.%2C%20Santaquiteria%2C%20A.%2C%20White%2C%20W.%20T.%2C%20Baldwin%2C%20C.%20C.%2C%20Miya%2C%20M.%2C%20Betancur-R%2C%20R.%2C%20Tornabene%2C%20L.%2C%20Evans%2C%20K.%2C%20%26amp%3B%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%20%282024%29.%20Reduced%20evolutionary%20constraint%20accompanies%20ongoing%20radiation%20in%20deep-sea%20anglerfishes.%20%3Ci%3ENature%20Ecology%20%26amp%3B%20Evolution%3C%5C%2Fi%3E.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41559-024-02586-3%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41559-024-02586-3%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Reduced%20evolutionary%20constraint%20accompanies%20ongoing%20radiation%20in%20deep-sea%20anglerfishes%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elizabeth%20Christina%22%2C%22lastName%22%3A%22Miller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rose%22%2C%22lastName%22%3A%22Faucher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pamela%20B.%22%2C%22lastName%22%3A%22Hart%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Melissa%22%2C%22lastName%22%3A%22Rinc%5Cu00f3n-Sandoval%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Aintzane%22%2C%22lastName%22%3A%22Santaquiteria%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22William%20T.%22%2C%22lastName%22%3A%22White%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carole%20C.%22%2C%22lastName%22%3A%22Baldwin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Masaki%22%2C%22lastName%22%3A%22Miya%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricardo%22%2C%22lastName%22%3A%22Betancur-R%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Luke%22%2C%22lastName%22%3A%22Tornabene%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kory%22%2C%22lastName%22%3A%22Evans%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dahiana%22%2C%22lastName%22%3A%22Arcila%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222024-11-27%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41559-024-02586-3%22%2C%22ISSN%22%3A%222397-334X%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41559-024-02586-3%22%2C%22collections%22%3A%5B%22BTBUS4GS%22%2C%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-12-23T17%3A43%3A47Z%22%7D%7D%2C%7B%22key%22%3A%22M9QD7W2J%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Rincon-Sandoval%20et%20al.%22%2C%22parsedDate%22%3A%222024-11-20%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ERincon-Sandoval%2C%20M.%2C%20De-Kayne%2C%20R.%2C%20Shank%2C%20S.%20D.%2C%20Pirro%2C%20S.%2C%20Ko%26%23x2019%3Bou%2C%20A.%2C%20Abueg%2C%20L.%2C%20Tracey%2C%20A.%2C%20Mountcastle%2C%20J.%2C%20O%26%23x2019%3BToole%2C%20B.%2C%20Balacco%2C%20J.%2C%20Formenti%2C%20G.%2C%20Jarvis%2C%20E.%20D.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20Kosakovsky%20Pond%2C%20S.%20L.%2C%20Davis%2C%20A.%2C%20Bloom%2C%20D.%20D.%2C%20%26amp%3B%20Betancur-R%2C%20R.%20%282024%29.%20Ecological%20diversification%20of%20sea%20catfishes%20is%20accompanied%20by%20genome-wide%20signatures%20of%20positive%20selection.%20%3Ci%3ENature%20Communications%3C%5C%2Fi%3E%2C%20%3Ci%3E15%3C%5C%2Fi%3E%281%29%2C%2010040.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41467-024-54184-3%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41467-024-54184-3%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Ecological%20diversification%20of%20sea%20catfishes%20is%20accompanied%20by%20genome-wide%20signatures%20of%20positive%20selection%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Melissa%22%2C%22lastName%22%3A%22Rincon-Sandoval%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rishi%22%2C%22lastName%22%3A%22De-Kayne%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephen%20D.%22%2C%22lastName%22%3A%22Shank%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stacy%22%2C%22lastName%22%3A%22Pirro%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alfred%22%2C%22lastName%22%3A%22Ko%5Cu2019ou%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Linelle%22%2C%22lastName%22%3A%22Abueg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alan%22%2C%22lastName%22%3A%22Tracey%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jackie%22%2C%22lastName%22%3A%22Mountcastle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Brian%22%2C%22lastName%22%3A%22O%5Cu2019Toole%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jennifer%22%2C%22lastName%22%3A%22Balacco%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Giulio%22%2C%22lastName%22%3A%22Formenti%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Erich%20D.%22%2C%22lastName%22%3A%22Jarvis%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dahiana%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sergei%20L.%22%2C%22lastName%22%3A%22Kosakovsky%20Pond%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Aaron%22%2C%22lastName%22%3A%22Davis%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Devin%20D.%22%2C%22lastName%22%3A%22Bloom%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricardo%22%2C%22lastName%22%3A%22Betancur-R%22%7D%5D%2C%22abstractNote%22%3A%22Abstract%5Cn%20%20%20%20%20%20%20%20%20%20%20%20Habitat%20transitions%20have%20shaped%20the%20evolutionary%20trajectory%20of%20many%20clades.%20Sea%20catfishes%20%28Ariidae%29%20have%20repeatedly%20undergone%20ecological%20transitions%2C%20including%20colonizing%20freshwaters%20from%20marine%20environments%2C%20leading%20to%20an%20adaptive%20radiation%20in%20Australia%20and%20New%20Guinea%20alongside%20non-radiating%20freshwater%20lineages%20elsewhere.%20Here%2C%20we%20generate%20and%20analyze%20one%20long-read%20reference%20genome%20and%2066%20short-read%20whole%20genome%20assemblies%2C%20in%20conjunction%20with%20genomic%20data%20for%2054%20additional%20species.%20We%20investigate%20how%20three%20major%20ecological%20transitions%20have%20shaped%20genomic%20variation%20among%20ariids%20over%20their%5Cu2009~%5Cu200950%5Cu2009million-year%20evolutionary%20history.%20Our%20results%20show%20that%20relatively%20younger%20freshwater%20lineages%20exhibit%20a%20higher%20incidence%20of%20positive%20selection%20than%20their%20more%20ancient%20marine%20counterparts.%20They%20also%20display%20a%20larger%20disparity%20in%20body%20shapes%2C%20a%20trend%20that%20correlates%20with%20a%20heightened%20occurrence%20of%20positive%20selection%20on%20genes%20associated%20with%20body%20size%20and%20elongation.%20Although%20positive%20selection%20in%20the%20Australia%20and%20New%20Guinea%20radiation%20does%20not%20stand%20out%20compared%20to%20non-radiating%20lineages%20overall%2C%20selection%20across%20the%20prolactin%20gene%20family%20during%20the%20marine-to-freshwater%20transition%20suggests%20that%20strong%20osmoregulatory%20adaptations%20may%20have%20facilitated%20their%20colonization%20and%20radiation.%20Our%20findings%20underscore%20the%20significant%20role%20of%20selection%20in%20shaping%20the%20genome%20and%20organismal%20traits%20in%20response%20to%20habitat%20shifts%20across%20macroevolutionary%20scales.%22%2C%22date%22%3A%222024-11-20%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41467-024-54184-3%22%2C%22ISSN%22%3A%222041-1723%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41467-024-54184-3%22%2C%22collections%22%3A%5B%22BTBUS4GS%22%2C%2276CNVERS%22%5D%2C%22dateModified%22%3A%222025-02-21T23%3A36%3A32Z%22%7D%7D%2C%7B%22key%22%3A%22W8YXJ777%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Troyer%20et%20al.%22%2C%22parsedDate%22%3A%222024-09-11%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ETroyer%2C%20E.%20M.%2C%20Evans%2C%20K.%20M.%2C%20Goatley%2C%20C.%20H.%20R.%2C%20Friedman%2C%20M.%2C%20Carnevale%2C%20G.%2C%20Nicholas%2C%20B.%2C%20Kolmann%2C%20M.%2C%20Bemis%2C%20K.%20E.%2C%20%26amp%3B%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%20%282024%29.%20Evolutionary%20innovation%20accelerates%20morphological%20diversification%20in%20pufferfishes%20and%20their%20relatives.%20%3Ci%3EEvolution%3C%5C%2Fi%3E%2C%20qpae127.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fevolut%5C%2Fqpae127%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fevolut%5C%2Fqpae127%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Evolutionary%20innovation%20accelerates%20morphological%20diversification%20in%20pufferfishes%20and%20their%20relatives%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Emily%20M%22%2C%22lastName%22%3A%22Troyer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kory%20M%22%2C%22lastName%22%3A%22Evans%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christopher%20H%20R%22%2C%22lastName%22%3A%22Goatley%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matt%22%2C%22lastName%22%3A%22Friedman%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Giorgio%22%2C%22lastName%22%3A%22Carnevale%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benjamin%22%2C%22lastName%22%3A%22Nicholas%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthew%22%2C%22lastName%22%3A%22Kolmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katherine%20E%22%2C%22lastName%22%3A%22Bemis%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dahiana%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22editor%22%2C%22firstName%22%3A%22Emma%22%2C%22lastName%22%3A%22Sherratt%22%7D%2C%7B%22creatorType%22%3A%22editor%22%2C%22firstName%22%3A%22H%5Cu00e9l%5Cu00e8ne%22%2C%22lastName%22%3A%22Morlon%22%7D%5D%2C%22abstractNote%22%3A%22Abstract%5Cn%20%20%20%20%20%20%20%20%20%20%20%20Evolutionary%20innovations%20have%20played%20an%20important%20role%20in%20shaping%20the%20diversity%20of%20life%20on%20Earth.%20However%2C%20how%20these%20innovations%20arise%20and%20their%20downstream%20effects%20on%20patterns%20of%20morphological%20diversification%20remain%20poorly%20understood.%20Here%2C%20we%20examine%20the%20impact%20of%20evolutionary%20innovation%20on%20trait%20diversification%20in%20tetraodontiform%20fishes%20%28pufferfishes%2C%20boxfishes%2C%20ocean%20sunfishes%2C%20and%20allies%29.%20This%20order%20provides%20an%20ideal%20model%20system%20for%20studying%20morphological%20diversification%20owing%20to%20their%20range%20of%20habitats%20and%20divergent%20morphologies%2C%20including%20the%20fusion%20of%20the%20teeth%20into%20a%20beak%20in%20several%20families.%20Using%20three-dimensional%20geometric%20morphometric%20data%20for%20176%20extant%20and%20fossil%20species%2C%20we%20examine%20the%20effect%20of%20skull%20integration%20and%20novel%20habitat%20association%20on%20the%20evolution%20of%20innovation.%20Strong%20integration%20may%20be%20a%20requirement%20for%20rapid%20trait%20evolution%20and%20facilitating%20the%20evolution%20of%20innovative%20structures%2C%20like%20the%20tetraodontiform%20beak.%20Our%20results%20show%20that%20the%20beak%20arose%20in%20the%20presence%20of%20highly%20conserved%20patterns%20of%20integration%20across%20the%20skull%2C%20suggesting%20that%20integration%20did%20not%20limit%20the%20range%20of%20available%20phenotypes%20to%20tetraodontiforms.%20Furthermore%2C%20we%20find%20that%20beaks%20have%20allowed%20tetraodontiforms%20to%20diversify%20into%20novel%20ecological%20niches%2C%20irrespective%20of%20habitat.%20Our%20results%20suggest%20that%20general%20rules%20pertaining%20to%20evolutionary%20innovation%20may%20be%20more%20nuanced%20than%20previously%20thought.%22%2C%22date%22%3A%222024-09-11%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1093%5C%2Fevolut%5C%2Fqpae127%22%2C%22ISSN%22%3A%220014-3820%2C%201558-5646%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Facademic.oup.com%5C%2Fevolut%5C%2Fadvance-article%5C%2Fdoi%5C%2F10.1093%5C%2Fevolut%5C%2Fqpae127%5C%2F7754972%22%2C%22collections%22%3A%5B%22F2MEDY88%22%2C%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-10-22T17%3A47%3A59Z%22%7D%7D%2C%7B%22key%22%3A%22FDUH4UY8%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Duarte-Ribeiro%20et%20al.%22%2C%22parsedDate%22%3A%222024-05-27%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EDuarte-Ribeiro%2C%20E.%2C%20Rosas-Puchuri%2C%20U.%2C%20Friedman%2C%20M.%2C%20Woodruff%2C%20G.%20C.%2C%20Hughes%2C%20L.%20C.%2C%20Carpenter%2C%20K.%20E.%2C%20White%2C%20W.%20T.%2C%20Pogonoski%2C%20J.%20J.%2C%20Westneat%2C%20M.%2C%20Diaz%20De%20Astarloa%2C%20J.%20M.%2C%20Williams%2C%20J.%20T.%2C%20Santos%2C%20M.%20D.%2C%20Dom%26%23xED%3Bnguez-Dom%26%23xED%3Bnguez%2C%20O.%2C%20Ort%26%23xED%3B%2C%20G.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20%26amp%3B%20Betancur-R%2C%20R.%20%282024%29.%20Phylogenomic%20and%20comparative%20genomic%20analyses%20support%20a%20single%20evolutionary%20origin%20of%20flatfish%20asymmetry.%20%3Ci%3ENature%20Genetics%3C%5C%2Fi%3E.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41588-024-01784-w%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41588-024-01784-w%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Phylogenomic%20and%20comparative%20genomic%20analyses%20support%20a%20single%20evolutionary%20origin%20of%20flatfish%20asymmetry%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Emanuell%22%2C%22lastName%22%3A%22Duarte-Ribeiro%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulises%22%2C%22lastName%22%3A%22Rosas-Puchuri%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matt%22%2C%22lastName%22%3A%22Friedman%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gavin%20C.%22%2C%22lastName%22%3A%22Woodruff%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lily%20C.%22%2C%22lastName%22%3A%22Hughes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kent%20E.%22%2C%22lastName%22%3A%22Carpenter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22William%20T.%22%2C%22lastName%22%3A%22White%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22John%20J.%22%2C%22lastName%22%3A%22Pogonoski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mark%22%2C%22lastName%22%3A%22Westneat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juan%20Martin%22%2C%22lastName%22%3A%22Diaz%20De%20Astarloa%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jeffrey%20T.%22%2C%22lastName%22%3A%22Williams%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mudjekeewis%20D.%22%2C%22lastName%22%3A%22Santos%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Omar%22%2C%22lastName%22%3A%22Dom%5Cu00ednguez-Dom%5Cu00ednguez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Guillermo%22%2C%22lastName%22%3A%22Ort%5Cu00ed%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dahiana%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricardo%22%2C%22lastName%22%3A%22Betancur-R%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222024-05-27%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41588-024-01784-w%22%2C%22ISSN%22%3A%221061-4036%2C%201546-1718%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41588-024-01784-w%22%2C%22collections%22%3A%5B%22BTBUS4GS%22%2C%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-06-10T20%3A58%3A47Z%22%7D%7D%2C%7B%22key%22%3A%229BRCD7YF%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Egan%20et%20al.%22%2C%22parsedDate%22%3A%222024-05-17%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EEgan%2C%20J.%20P.%2C%20Simons%2C%20A.%20M.%2C%20Alavi-Yeganeh%2C%20M.%20S.%2C%20Hammer%2C%20M.%20P.%2C%20Tongnunui%2C%20P.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20Betancur-R%2C%20R.%2C%20%26amp%3B%20Bloom%2C%20D.%20D.%20%282024%29.%20Phylogenomics%2C%20Lineage%20Diversification%20Rates%2C%20and%20the%20Evolution%20of%20Diadromy%20in%20Clupeiformes%20%28Anchovies%2C%20Herrings%2C%20Sardines%2C%20and%20Relatives%29.%20%3Ci%3ESystematic%20Biology%3C%5C%2Fi%3E%2C%20syae022.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fsysbio%5C%2Fsyae022%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fsysbio%5C%2Fsyae022%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Phylogenomics%2C%20Lineage%20Diversification%20Rates%2C%20and%20the%20Evolution%20of%20Diadromy%20in%20Clupeiformes%20%28Anchovies%2C%20Herrings%2C%20Sardines%2C%20and%20Relatives%29%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joshua%20P%22%2C%22lastName%22%3A%22Egan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andrew%20M%22%2C%22lastName%22%3A%22Simons%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mohammad%20Sadegh%22%2C%22lastName%22%3A%22Alavi-Yeganeh%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%20P%22%2C%22lastName%22%3A%22Hammer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Prasert%22%2C%22lastName%22%3A%22Tongnunui%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dahiana%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricardo%22%2C%22lastName%22%3A%22Betancur-R%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Devin%20D%22%2C%22lastName%22%3A%22Bloom%22%7D%2C%7B%22creatorType%22%3A%22editor%22%2C%22firstName%22%3A%22James%22%2C%22lastName%22%3A%22Albert%22%7D%5D%2C%22abstractNote%22%3A%22Abstract%5Cn%20%20%20%20%20%20%20%20%20%20%20%20Migration%20independently%20evolved%20numerous%20times%20in%20animals%2C%20with%20a%20myriad%20of%20ecological%20and%20evolutionary%20implications.%20In%20fishes%2C%20perhaps%20the%20most%20extreme%20form%20of%20migration%20is%20diadromy%2C%20the%20migration%20between%20marine%20and%20freshwater%20environments.%20Key%20and%20long-standing%20questions%20are%3A%20how%20many%20times%20has%20diadromy%20evolved%20in%20fishes%2C%20how%20frequently%20do%20diadromous%20clades%20give%20rise%20to%20non-diadromous%20species%2C%20and%20does%20diadromy%20influence%20lineage%20diversification%20rates%3F%20Many%20diadromous%20fishes%20have%20large%20geographic%20ranges%20with%20constituent%20populations%20that%20use%20isolated%20freshwater%20habitats.%20This%20may%20limit%20gene%20flow%20between%20some%20populations%2C%20increasing%20the%20likelihood%20of%20speciation%20in%20diadromous%20lineages%20relative%20to%20nondiadromous%20lineages.%20Alternatively%2C%20diadromy%20may%20reduce%20lineage%20diversification%20rates%20if%20migration%20is%20associated%20with%20enhanced%20dispersal%20capacity%20that%20facilitates%20gene%20flow%20within%20and%20between%20populations.%20Clupeiformes%20%28herrings%2C%20sardines%2C%20shads%2C%20and%20anchovies%29%20is%20a%20model%20clade%20for%20testing%20hypotheses%20about%20the%20evolution%20of%20diadromy%20because%20it%20includes%20an%20exceptionally%20high%20proportion%20of%20diadromous%20species%20and%20several%20independent%20evolutionary%20origins%20of%20diadromy.%20However%2C%20relationships%20among%20major%20clupeiform%20lineages%20remain%20unresolved%2C%20and%20existing%20phylogenies%20sparsely%20sampled%20diadromous%20species%2C%20limiting%20the%20resolution%20of%20phylogenetically%20informed%20statistical%20analyses.%20We%20assembled%20a%20phylogenomic%20dataset%20and%20used%20multi-species%20coalescent%20and%20concatenation-based%20approaches%20to%20generate%20the%20most%20comprehensive%2C%20highly%20resolved%20clupeiform%20phylogeny%20to%20date%2C%20clarifying%20associations%20among%20several%20major%20clades%20and%20identifying%20recalcitrant%20relationships%20needing%20further%20examination.%20We%20determined%20that%20variation%20in%20rates%20of%20sequence%20evolution%20%28heterotachy%29%20and%20base-composition%20%28nonstationarity%29%20had%20little%20impact%20on%20our%20results.%20Using%20this%20phylogeny%2C%20we%20characterized%20evolutionary%20patterns%20of%20diadromy%20and%20tested%20for%20differences%20in%20lineage%20diversification%20rates%20between%20diadromous%2C%20marine%2C%20and%20freshwater%20lineages.%20We%20identified%2013%20transitions%20to%20diadromy%2C%20all%20during%20the%20Cenozoic%20Era%20%2810%20origins%20of%20anadromy%2C%202%20origins%20of%20catadromy%2C%20and%201%20origin%20of%20amphidromy%29%2C%20and%207%20losses%20of%20diadromy.%20Two%20diadromous%20lineages%20rapidly%20generated%20nondiadromous%20species%2C%20demonstrating%20that%20diadromy%20is%20not%20an%20evolutionary%20dead%20end.%20We%20discovered%20considerably%20faster%20transition%20rates%20out%20of%20diadromy%20than%20to%20diadromy.%20The%20largest%20lineage%20diversification%20rate%20increase%20in%20Clupeiformes%20was%20associated%20with%20a%20transition%20to%20diadromy%2C%20but%20we%20uncovered%20little%20statistical%20support%20for%20categorically%20faster%20lineage%20diversification%20rates%20in%20diadromous%20versus%20nondiadromous%20fishes.%20We%20propose%20that%20diadromy%20may%20increase%20the%20potential%20for%20accelerated%20lineage%20diversification%2C%20particularly%20in%20species%20that%20migrate%20long%20distances.%20However%2C%20this%20potential%20may%20only%20be%20realized%20in%20certain%20biogeographic%20contexts%2C%20such%20as%20when%20diadromy%20allows%20access%20to%20ecosystems%20in%20which%20there%20is%20limited%20competition%20from%20incumbent%20species.%22%2C%22date%22%3A%222024-05-17%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1093%5C%2Fsysbio%5C%2Fsyae022%22%2C%22ISSN%22%3A%221063-5157%2C%201076-836X%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Facademic.oup.com%5C%2Fsysbio%5C%2Fadvance-article%5C%2Fdoi%5C%2F10.1093%5C%2Fsysbio%5C%2Fsyae022%5C%2F7675602%22%2C%22collections%22%3A%5B%22BTBUS4GS%22%2C%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-10-14T17%3A13%3A40Z%22%7D%7D%2C%7B%22key%22%3A%22S8TMZDD3%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Mihali%5Cu010d%20et%20al.%22%2C%22parsedDate%22%3A%222024-02-01%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EMihali%26%23x10D%3B%2C%20F.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20Pettersson%2C%20M.%20E.%2C%20Farkhondehkish%2C%20P.%2C%20Andersson%2C%20E.%2C%20Andersson%2C%20L.%2C%20Betancur-R%2C%20R.%2C%20%26amp%3B%20Jemth%2C%20P.%20%282024%29.%20Conservation%20of%20affinity%20rather%20than%20sequence%20underlies%20a%20dynamic%20evolution%20of%20the%20motif-mediated%20p53%5C%2FMDM2%20interaction%20in%20ray-finned%20fishes.%20%3Ci%3EMolecular%20Biology%20and%20Evolution%3C%5C%2Fi%3E%2C%20msae018.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fmolbev%5C%2Fmsae018%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fmolbev%5C%2Fmsae018%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Conservation%20of%20affinity%20rather%20than%20sequence%20underlies%20a%20dynamic%20evolution%20of%20the%20motif-mediated%20p53%5C%2FMDM2%20interaction%20in%20ray-finned%20fishes%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Filip%22%2C%22lastName%22%3A%22Mihali%5Cu010d%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dahiana%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mats%20E%22%2C%22lastName%22%3A%22Pettersson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pouria%22%2C%22lastName%22%3A%22Farkhondehkish%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eva%22%2C%22lastName%22%3A%22Andersson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Leif%22%2C%22lastName%22%3A%22Andersson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricardo%22%2C%22lastName%22%3A%22Betancur-R%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Per%22%2C%22lastName%22%3A%22Jemth%22%7D%2C%7B%22creatorType%22%3A%22editor%22%2C%22firstName%22%3A%22Mary%22%2C%22lastName%22%3A%22O%27Connell%22%7D%5D%2C%22abstractNote%22%3A%22Abstract%5Cn%20%20%20%20%20%20%20%20%20%20%20%20The%20transcription%20factor%20and%20cell%20cycle%20regulator%20p53%20is%20marked%20for%20degradation%20by%20the%20ubiquitin%20ligase%20MDM2.%20The%20interaction%20between%20these%20two%20proteins%20is%20mediated%20by%20a%20conserved%20binding%20motif%20in%20the%20disordered%20p53%20transactivation%20domain%20%28p53TAD%29%20and%20the%20folded%20SWIB%20domain%20in%20MDM2.%20The%20conserved%20motif%20in%20p53TAD%20from%20zebrafish%20displays%20a%2020-fold%20weaker%20interaction%20with%20MDM2%2C%20compared%20to%20the%20interaction%20in%20human%20and%20chicken.%20To%20investigate%20this%20apparent%20difference%2C%20we%20tracked%20the%20molecular%20evolution%20of%20the%20p53TAD%5C%2FMDM2%20interaction%20among%20ray-finned%20fishes%20%28Actinopterygii%29%2C%20the%20largest%20vertebrate%20clade.%20Intriguingly%2C%20phylogenetic%20analyses%2C%20ancestral%20sequence%20reconstructions%2C%20and%20binding%20experiments%20showed%20that%20different%20loss-of-affinity%20changes%20in%20the%20canonical%20binding%20motif%20within%20p53TAD%20have%20occurred%20repeatedly%20and%20convergently%20in%20different%20fish%20lineages%2C%20resulting%20in%20relatively%20low%20extant%20affinities%20%28KD%5Cu2009%3D%5Cu20090.5-5%5Cu2005%5Cu03bcM%29.%20However%2C%20for%20eleven%20different%20fish%20p53TAD%5C%2FMDM2%20interactions%2C%20non-conserved%20regions%20flanking%20the%20canonical%20motif%20increased%20the%20affinity%204%20to%2073-fold%20to%20be%20on%20par%20with%20the%20human%20interaction.%20Our%20findings%20suggest%20that%20compensating%20changes%20at%20conserved%20and%20non-conserved%20positions%20within%20the%20motif%2C%20as%20well%20as%20in%20flanking%20regions%20of%20low%20conservation%2C%20underlie%20a%20stabilizing%20selection%20of%20%5Cu201cfunctional%20affinity%5Cu201d%20in%20the%20p53TAD%5C%2FMDM2%20interaction.%20Such%20interplay%20complicates%20bioinformatic%20prediction%20of%20binding%20and%20call%20for%20experimental%20validation.%20Motif-mediated%20protein-protein%20interactions%20involving%20short%20binding%20motifs%20and%20folded%20interaction%20domains%20are%20very%20common%20across%20multicellular%20life.%20It%20is%20likely%20that%20evolution%20of%20affinity%20in%20motif-mediated%20interactions%20often%20involves%20an%20interplay%20between%20specific%20interactions%20made%20by%20conserved%20motif%20residues%20and%20non-specific%20interactions%20by%20non-conserved%20disordered%20regions.%22%2C%22date%22%3A%222024-02-01%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1093%5C%2Fmolbev%5C%2Fmsae018%22%2C%22ISSN%22%3A%220737-4038%2C%201537-1719%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Facademic.oup.com%5C%2Fmbe%5C%2Fadvance-article%5C%2Fdoi%5C%2F10.1093%5C%2Fmolbev%5C%2Fmsae018%5C%2F7596109%22%2C%22collections%22%3A%5B%22BTBUS4GS%22%2C%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-02-27T00%3A31%3A58Z%22%7D%7D%2C%7B%22key%22%3A%2299HMB4PT%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Drabeck%20et%20al.%22%2C%22parsedDate%22%3A%222024%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EDrabeck%2C%20D.%20H.%2C%20Wiese%2C%20J.%2C%20Gilbertson%2C%20E.%2C%20Arroyave%2C%20J.%2C%20Stiassny%2C%20M.%20L.%20J.%2C%20Alter%2C%20S.%20E.%2C%20Borowsky%2C%20R.%2C%20Hendrickson%2C%20D.%20A.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20%26amp%3B%20McGaugh%2C%20S.%20E.%20%282024%29.%20Gene%20loss%20and%20relaxed%20selection%20of%20%3Ci%3Eplaat1%3C%5C%2Fi%3E%20in%20vertebrates%20adapted%20to%20low-light%20environments.%20%3Ci%3EProceedings%20of%20the%20Royal%20Society%20B%3A%20Biological%20Sciences%3C%5C%2Fi%3E%2C%20%3Ci%3E291%3C%5C%2Fi%3E%282024%29%2C%2020232847.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1098%5C%2Frspb.2023.2847%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1098%5C%2Frspb.2023.2847%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Gene%20loss%20and%20relaxed%20selection%20of%20%3Ci%3Eplaat1%3C%5C%2Fi%3E%20in%20vertebrates%20adapted%20to%20low-light%20environments%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Danielle%20H.%22%2C%22lastName%22%3A%22Drabeck%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jonathan%22%2C%22lastName%22%3A%22Wiese%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Erin%22%2C%22lastName%22%3A%22Gilbertson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jairo%22%2C%22lastName%22%3A%22Arroyave%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Melanie%20L.%20J.%22%2C%22lastName%22%3A%22Stiassny%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S.%20Elizabeth%22%2C%22lastName%22%3A%22Alter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Richard%22%2C%22lastName%22%3A%22Borowsky%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dean%20A.%22%2C%22lastName%22%3A%22Hendrickson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dahiana%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Suzanne%20E.%22%2C%22lastName%22%3A%22McGaugh%22%7D%5D%2C%22abstractNote%22%3A%22Gene%20loss%20is%20an%20important%20mechanism%20for%20evolution%20in%20low-light%20or%20cave%20environments%20where%20visual%20adaptations%20often%20involve%20a%20reduction%20or%20loss%20of%20eyesight.%20The%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20plaat%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20gene%20family%20encodes%20phospholipases%20essential%20for%20the%20degradation%20of%20organelles%20in%20the%20lens%20of%20the%20eye.%20These%20phospholipases%20translocate%20to%20damaged%20organelle%20membranes%2C%20inducing%20them%20to%20rupture.%20This%20rupture%20is%20required%20for%20lens%20transparency%20and%20is%20essential%20for%20developing%20a%20functioning%20eye.%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Plaat3%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20is%20thought%20to%20be%20responsible%20for%20this%20role%20in%20mammals%2C%20while%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20plaat1%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20is%20thought%20to%20be%20responsible%20in%20other%20vertebrates.%20We%20used%20a%20macroevolutionary%20approach%20and%20comparative%20genomics%20to%20examine%20the%20origin%2C%20loss%2C%20synteny%20and%20selection%20of%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20plaat1%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20across%20bony%20fishes%20and%20tetrapods.%20We%20showed%20that%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20plaat1%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%28probably%20ancestral%20to%20all%20bony%20fish%20%2B%20tetrapods%29%20has%20been%20lost%20in%20squamates%20and%20is%20significantly%20degraded%20in%20lineages%20of%20low-visual-acuity%20and%20blind%20mammals%20and%20fishes.%20Our%20findings%20suggest%20that%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20plaat1%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20is%20important%20for%20visual%20acuity%20across%20bony%20vertebrates%2C%20and%20that%20its%20loss%20through%20relaxed%20selection%20and%20pseudogenization%20may%20have%20played%20a%20role%20in%20the%20repeated%20evolution%20of%20visual%20systems%20in%20low-light%20environments.%20Our%20study%20sheds%20light%20on%20the%20importance%20of%20gene-loss%20in%20trait%20evolution%20and%20provides%20insights%20into%20the%20mechanisms%20underlying%20visual%20acuity%20in%20low-light%20environments.%22%2C%22date%22%3A%2206%5C%2F2024%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1098%5C%2Frspb.2023.2847%22%2C%22ISSN%22%3A%220962-8452%2C%201471-2954%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Froyalsocietypublishing.org%5C%2Fdoi%5C%2F10.1098%5C%2Frspb.2023.2847%22%2C%22collections%22%3A%5B%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-07-12T18%3A14%3A02Z%22%7D%7D%2C%7B%22key%22%3A%22IYM32ZDT%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Heiple%20et%20al.%22%2C%22parsedDate%22%3A%222023-06-28%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EHeiple%2C%20Z.%2C%20Huie%2C%20J.%20M.%2C%20Medeiros%2C%20A.%20P.%20M.%2C%20Hart%2C%20P.%20B.%2C%20Goatley%2C%20C.%20H.%20R.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20%26amp%3B%20Miller%2C%20E.%20C.%20%282023%29.%20Many%20ways%20to%20build%20an%20angler%3A%20diversity%20of%20feeding%20morphologies%20in%20a%20deep-sea%20evolutionary%20radiation.%20%3Ci%3EBiology%20Letters%3C%5C%2Fi%3E%2C%20%3Ci%3E19%3C%5C%2Fi%3E%286%29.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2FARTN%2020230049%2010.1098%5C%2Frsbl.2023.0049%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2FARTN%2020230049%2010.1098%5C%2Frsbl.2023.0049%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Many%20ways%20to%20build%20an%20angler%3A%20diversity%20of%20feeding%20morphologies%20in%20a%20deep-sea%20evolutionary%20radiation%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Z.%22%2C%22lastName%22%3A%22Heiple%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20M.%22%2C%22lastName%22%3A%22Huie%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%20P.%20M.%22%2C%22lastName%22%3A%22Medeiros%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22P.%20B.%22%2C%22lastName%22%3A%22Hart%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%20H.%20R.%22%2C%22lastName%22%3A%22Goatley%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22E.%20C.%22%2C%22lastName%22%3A%22Miller%22%7D%5D%2C%22abstractNote%22%3A%22Almost%20nothing%20is%20known%20about%20the%20diets%20of%20bathypelagic%20fishes%2C%20but%20functional%20morphology%20can%20provide%20useful%20tools%20to%20infer%20ecology.%20Here%20we%20quantify%20variation%20in%20jaw%20and%20tooth%20morphologies%20across%20anglerfishes%20%28Lophiiformes%29%2C%20a%20clade%20spanning%20shallow%20and%20deep-sea%20habitats.%20Deep-sea%20ceratioid%20anglerfishes%20are%20considered%20dietary%20generalists%20due%20to%20the%20necessity%20of%20opportunistic%20feeding%20in%20the%20food-limited%20bathypelagic%20zone.%20We%20found%20unexpected%20diversity%20in%20the%20trophic%20morphologies%20of%20ceratioid%20anglerfishes.%20Ceratioid%20jaws%20span%20a%20functional%20continuum%20ranging%20from%20species%20with%20numerous%20stout%20teeth%2C%20a%20relatively%20slow%20but%20forceful%20bite%2C%20and%20high%20jaw%20protrusibility%20at%20one%20end%20%28characteristics%20shared%20with%20benthic%20anglerfishes%29%20to%20species%20with%20long%20fang-like%20teeth%2C%20a%20fast%20but%20weak%20bite%20and%20low%20jaw%20protrusibility%20at%20the%20other%20end%20%28including%20a%20unique%20%27wolftrap%27%20phenotype%29.%20Our%20finding%20of%20high%20morphological%20diversity%20seems%20to%20be%20at%20odds%20with%20ecological%20generality%2C%20reminiscent%20of%20Liem%27s%20paradox%20%28morphological%20specialization%20allowing%20organisms%20to%20have%20broader%20niches%29.%20Another%20possible%20explanation%20is%20that%20diverse%20ceratioid%20functional%20morphologies%20may%20yield%20similar%20trophic%20success%20%28many-to-one%20mapping%20of%20morphology%20to%20diet%29%2C%20allowing%20diversity%20to%20arise%20through%20neutral%20evolutionary%20processes.%20Our%20results%20highlight%20that%20there%20are%20many%20ways%20to%20be%20a%20successful%20predator%20in%20the%20deep%20sea.%22%2C%22date%22%3A%22Jun%2028%202023%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%22ARTN%2020230049%2010.1098%5C%2Frsbl.2023.0049%22%2C%22ISSN%22%3A%221744-9561%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22RSUG6GEG%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Arcila%20et%20al.%22%2C%22parsedDate%22%3A%222023-05-19%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3E%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20Rincon-Sandoval%2C%20M.%2C%20Hanson%2C%20W.%2C%20Hart%2C%20P.%20B.%2C%20Gonz%26%23xE1%3Blez%2C%20V.%20L.%2C%20Betancur-R%2C%20R.%2C%20%26amp%3B%20Bichuette%2C%20M.%20E.%20%282023%29.%20Transcriptomic%20analysis%20of%20the%20Brazilian%20blind%20characid%2C%20Stygichthys%20typhlops%2C%20reveals%20convergent%20selection%20with%20Astyanax%20mexicanus%20and%20other%20cavefishes.%20%3Ci%3EFrontiers%20in%20Ecology%20and%20Evolution%3C%5C%2Fi%3E%2C%20%3Ci%3E11%3C%5C%2Fi%3E%2C%201076756.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Ffevo.2023.1076756%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Ffevo.2023.1076756%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Transcriptomic%20analysis%20of%20the%20Brazilian%20blind%20characid%2C%20Stygichthys%20typhlops%2C%20reveals%20convergent%20selection%20with%20Astyanax%20mexicanus%20and%20other%20cavefishes%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dahiana%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Melissa%22%2C%22lastName%22%3A%22Rincon-Sandoval%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22William%22%2C%22lastName%22%3A%22Hanson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pamela%20B.%22%2C%22lastName%22%3A%22Hart%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vanessa%20L.%22%2C%22lastName%22%3A%22Gonz%5Cu00e1lez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricardo%22%2C%22lastName%22%3A%22Betancur-R%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maria%20E.%22%2C%22lastName%22%3A%22Bichuette%22%7D%5D%2C%22abstractNote%22%3A%22Molecular%20studies%20have%20shown%20that%20Neotropical%20fishes%20of%20the%20order%20Characiformes%20have%20undergone%20two%20independent%20events%20of%20cave%20colonization.%20Among%20these%20fishes%20are%20the%20Mexican%20blind%20cavefish%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Astyanax%20mexicanus%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%29%2C%20a%20well-studied%20model%20system%20for%20cave%20adaptation%2C%20and%20the%20lesser-known%20Brazilian%20blind%20characid%20%28%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20Stygichthys%20typhlops%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%29.%20Although%20various%20genomic%20and%20transcriptomic%20approaches%20have%20been%20used%20to%20identify%20genes%20responsible%20for%20cave%20adaptation%20in%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20A.%20mexicanus%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20%2C%20these%20genetic%20factors%20have%20not%20been%20explored%20in%20an%20evolutionary%20comparative%20framework%20in%20cave-adapted%20characiforms.%20To%20address%20this%20gap%2C%20we%20assembled%20a%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20de%20novo%5Cn%20%20%20%20%20%20%20%20%20%20%20%20%20%20transcriptome%20for%20the%20Brazilian%20blind%20characid%2C%20identifying%2027%2C845%20assembled%20unigenes%2C%20of%20which%2022%2C580%20were%20assigned%20as%20putative%20one-to-one%20orthologs%20to%20the%20Mexican%20cavefish.%20We%20then%20used%20the%20package%20RELAX%20to%20analyze%20789%20genes%20in%20cavefishes%2C%20identifying%20311%20genes%20under%20intensified%20or%20relaxed%20selection.%20Our%20analysis%20revealed%2026%20genes%20with%20signatures%20of%20convergent%2C%20relaxed%20selection%20linked%20to%20vision%2C%20circadian%20cycles%2C%20pigmentation%2C%20and%20hematopoiesis%20processes.%20Additionally%2C%20we%20conducted%20differential%20gene%20expression%20analyzes%20between%20the%20snout%20region%20and%20a%20control%20tissue%20sample%20%28muscle%29%2C%20identifying%2096%20differentially%20expressed%20genes%20associated%20with%20cell-surface-bound%20and%20calcium-binding%20proteins.%20Our%20study%20offers%20insights%20into%20the%20genetic%20mechanisms%20underlying%20cave%20adaptation%20in%20characiform%20fishes%2C%20particularly%20the%20Brazilian%20blind%20characid.%20Moreover%2C%20our%20transcriptome%20dataset%20and%20list%20of%20genes%20under%20convergent%2C%20relaxed%2C%20and%20intensified%20selection%20serve%20as%20a%20valuable%20resource%20for%20future%20functional%20studies%20of%20genes%20involved%20in%20cave%20adaptation.%20Our%20work%20highlights%20the%20importance%20of%20examining%20genetic%20adaptations%20in%20multiple%20independent%20lineages%20to%20better%20understand%20the%20evolutionary%20processes%20underlying%20cave%20adaptation.%22%2C%22date%22%3A%222023-5-19%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.3389%5C%2Ffevo.2023.1076756%22%2C%22ISSN%22%3A%222296-701X%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.frontiersin.org%5C%2Farticles%5C%2F10.3389%5C%2Ffevo.2023.1076756%5C%2Ffull%22%2C%22collections%22%3A%5B%22BTBUS4GS%22%2C%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-16T23%3A55%3A48Z%22%7D%7D%2C%7B%22key%22%3A%22SN83AFLF%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Baldwin%20et%20al.%22%2C%22parsedDate%22%3A%222023-04-13%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBaldwin%2C%20C.%20C.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20Robertson%2C%20D.%20R.%2C%20%26amp%3B%20Tornabene%2C%20L.%20%282023%29.%20Description%20of%20the%20First%20Species%20of%20Polylepion%20%28Teleostei%3A%20Labridae%29%20from%20the%20Atlantic%20Ocean%20with%20Analysis%20of%20Evolutionary%20Relationships%20of%20the%20New%20Species.%20%3Ci%3EIchthyology%20%26amp%3B%20Herpetology%3C%5C%2Fi%3E%2C%20%3Ci%3E111%3C%5C%2Fi%3E%282%29.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1643%5C%2Fi2022075%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1643%5C%2Fi2022075%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Description%20of%20the%20First%20Species%20of%20Polylepion%20%28Teleostei%3A%20Labridae%29%20from%20the%20Atlantic%20Ocean%20with%20Analysis%20of%20Evolutionary%20Relationships%20of%20the%20New%20Species%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carole%20C.%22%2C%22lastName%22%3A%22Baldwin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dahiana%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%20Ross%22%2C%22lastName%22%3A%22Robertson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Luke%22%2C%22lastName%22%3A%22Tornabene%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222023-4-13%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1643%5C%2Fi2022075%22%2C%22ISSN%22%3A%222766-1512%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fbioone.org%5C%2Fjournals%5C%2Fichthyology-and-herpetology%5C%2Fvolume-111%5C%2Fissue-2%5C%2Fi2022075%5C%2FDescription-of-the-First-Species-of-Polylepion-Teleostei--Labridae%5C%2F10.1643%5C%2Fi2022075.full%22%2C%22collections%22%3A%5B%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-16T23%3A55%3A54Z%22%7D%7D%2C%7B%22key%22%3A%226GYUTWP6%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Collins%20et%20al.%22%2C%22parsedDate%22%3A%222023-04-11%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ECollins%2C%20Q.%20P.%2C%20Grunsted%2C%20M.%20J.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20Xiong%2C%20Y.%2C%20%26amp%3B%20Barmchi%2C%20M.%20P.%20%282023%29.%20Transcriptomic%20analysis%20provides%20insight%20into%20the%20mechanism%20of%20IKK%26%23x3B2%3B-mediated%20suppression%20of%20HPV18E6-induced%20cellular%20abnormalities.%20%3Ci%3EG3-Genes%20Genomes%20Genetics%3C%5C%2Fi%3E%2C%20%3Ci%3E13%3C%5C%2Fi%3E%284%29.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fg3journal%5C%2Fjkad020%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fg3journal%5C%2Fjkad020%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Transcriptomic%20analysis%20provides%20insight%20into%20the%20mechanism%20of%20IKK%5Cu03b2-mediated%20suppression%20of%20HPV18E6-induced%20cellular%20abnormalities%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Q.%20P.%22%2C%22lastName%22%3A%22Collins%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%20J.%22%2C%22lastName%22%3A%22Grunsted%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Y.%22%2C%22lastName%22%3A%22Xiong%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%20P.%22%2C%22lastName%22%3A%22Barmchi%22%7D%5D%2C%22abstractNote%22%3A%22High-risk%20human%20papillomaviruses%20%28HPVs%29%2016%20and%2018%20are%20responsible%20for%20more%20than%2070%25%20of%20cervical%20cancers%20and%20majority%20of%20other%20HPV-associated%20cancers%20world-wide.%20Current%20treatments%20for%20these%20cancers%20have%20limited%20efficacy%2C%20which%20in%20turn%20has%20resulted%20in%20disease%20recurrence%20and%20poor%20survival%20rates%20in%20advanced%20disease%20stages.%20Hence%2C%20there%20is%20a%20significant%20need%20for%20development%20of%20novel%20molecularly-targeted%20therapeutics.%20This%20can%20only%20be%20achieved%20through%20improved%20understanding%20of%20disease%20mechanism.%20Recently%2C%20we%20developed%20a%20Drosophila%20model%20of%20HPV18E6%20plus%20human%20E3%20ubiquitin%20ligase%20%28hUBE3A%29%20and%20demonstrated%20that%20the%20E6-induced%20cellular%20abnormalities%20are%20conserved%20between%20humans%20and%20flies.%20Subsequently%2C%20we%20demonstrated%20that%20reduced%20level%20and%20activity%20of%20IKK%20beta%2C%20a%20regulator%20of%20NF-kappa%20B%2C%20suppresses%20the%20cellular%20abnormalities%20induced%20by%20E6%20oncoprotein%20and%20that%20the%20interaction%20of%20IKK%20beta%20and%20E6%20is%20conserved%20in%20human%20cells.%20In%20this%20study%2C%20we%20performed%20transcriptomic%20analysis%20to%20identify%20differentially%20expressed%20genes%20that%20play%20a%20role%20in%20IKK%20beta-mediated%20suppression%20of%20E6-induced%20defects.%20Transcriptome%20analysis%20identified%20215%20genes%20whose%20expression%20was%20altered%20due%20to%20reduced%20levels%20of%20IKK%20beta.%20Of%20these%20215%20genes%2C%20151%20genes%20showed%20annotations.%20These%20analyses%20were%20followed%20by%20functional%20genetic%20interaction%20screen%20using%20RNAi%2C%20overexpression%2C%20and%20mutant%20fly%20strains%20for%20identified%20genes.%20The%20screen%20identified%20several%20genes%20including%20genes%20involved%20in%20Hippo%20and%20Toll%20pathways%20as%20well%20as%20junctional%20complexes%20whose%20downregulation%20or%20upregulation%20resulted%20in%20alterations%20of%20E6-induced%20defects.%20Subsequently%2C%20RT-PCR%20analysis%20was%20performed%20for%20validation%20of%20altered%20gene%20expression%20level%20for%20a%20few%20representative%20genes.%20Our%20results%20indicate%20an%20involvement%20for%20Hippo%20and%20Toll%20pathways%20in%20IKK%20beta-mediated%20suppression%20of%20E6%20%2B%20hUBE3A-induced%20cellular%20abnormalities.%20Therefore%2C%20this%20study%20enhances%20our%20understanding%20of%20the%20mechanisms%20underlying%20HPV-induced%20cancer%20and%20can%20potentially%20lead%20to%20identification%20of%20novel%20drug%20targets%20for%20cancers%20associated%20with%20HPV.%22%2C%22date%22%3A%22Apr%2011%202023%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%2210.1093%5C%2Fg3journal%5C%2Fjkad020%22%2C%22ISSN%22%3A%222160-1836%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22A8KIDJMS%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Peterson%20et%20al.%22%2C%22parsedDate%22%3A%222022-08-10%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPeterson%2C%20R.%20D.%2C%20Sullivan%2C%20J.%20P.%2C%20Hopkins%2C%20C.%20D.%2C%20Santaquiteria%2C%20A.%2C%20Dillman%2C%20C.%20B.%2C%20Pirro%2C%20S.%2C%20Betancur-R%2C%20R.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20Hughes%2C%20L.%20C.%2C%20%26amp%3B%20Ort%26%23xED%3B%2C%20G.%20%282022%29.%20Phylogenomics%20of%20Bony-Tongue%20Fishes%20%28Osteoglossomorpha%29%20Shed%20Light%20on%20the%20Craniofacial%20Evolution%20and%20Biogeography%20of%20the%20Weakly%20Electric%20Clade%20%28Mormyridae%29.%20%3Ci%3ESystematic%20Biology%3C%5C%2Fi%3E%2C%20%3Ci%3E71%3C%5C%2Fi%3E%285%29%2C%201032%26%23x2013%3B1044.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fsysbio%5C%2Fsyac001%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fsysbio%5C%2Fsyac001%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Phylogenomics%20of%20Bony-Tongue%20Fishes%20%28Osteoglossomorpha%29%20Shed%20Light%20on%20the%20Craniofacial%20Evolution%20and%20Biogeography%20of%20the%20Weakly%20Electric%20Clade%20%28Mormyridae%29%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%20D.%22%2C%22lastName%22%3A%22Peterson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20P.%22%2C%22lastName%22%3A%22Sullivan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%20D.%22%2C%22lastName%22%3A%22Hopkins%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Santaquiteria%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%20B.%22%2C%22lastName%22%3A%22Dillman%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S.%22%2C%22lastName%22%3A%22Pirro%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Betancur-R%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22L.%20C.%22%2C%22lastName%22%3A%22Hughes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Ort%5Cu00ed%22%7D%5D%2C%22abstractNote%22%3A%22Bonytongues%20%28Osteoglossomorpha%29%20constitute%20an%20ancient%20clade%20of%20teleost%20fishes%20distributed%20in%20freshwater%20habitats%20throughout%20the%20world.%20The%20group%20includes%20well-known%20species%20such%20as%20arowanas%2C%20featherbacks%2C%20pirarucus%2C%20and%20the%20weakly%20electric%20fishes%20in%20the%20family%20Mormyridae.%20Their%20disjunct%20distribution%2C%20extreme%20morphologies%2C%20and%20electrolocating%20capabilities%20%28Gymnarchidae%20and%20Mormyridae%29%20have%20attracted%20much%20scientific%20interest%2C%20but%20a%20comprehensive%20phylogenetic%20framework%20for%20comparative%20analysis%20is%20missing%2C%20especially%20for%20the%20species-rich%20family%20Mormyridae.%20Of%20particular%20interest%20are%20disparate%20craniofacial%20morphologies%20among%20mormyrids%20which%20might%20constitute%20an%20exceptional%20model%20system%20to%20study%20convergent%20evolution.%20We%20present%20a%20phylogenomic%20analysis%20based%20on%20546%20exons%20of%20179%20species%20%28out%20of%20260%29%2C%2028%20out%20of%2029%20genera%2C%20and%20all%20six%20families%20of%20extant%20bonytongues.%20Based%20on%20a%20recent%20reassessment%20of%20the%20fossil%20record%20of%20osteoglossomorphs%2C%20we%20inferred%20dates%20of%20divergence%20among%20transcontinental%20clades%20and%20the%20major%20groups.%20The%20estimated%20ages%20of%20divergence%20among%20extant%20taxa%20%28e.g.%2C%20Osteoglossomorpha%2C%20Osteoglossiformes%2C%20and%20Mormyroidea%29%20are%20older%20than%20previous%20reports%2C%20but%20most%20of%20the%20divergence%20dates%20obtained%20for%20clades%20on%20separate%20continents%20are%20too%20young%20to%20be%20explained%20by%20simple%20vicariance%20hypotheses.%20Biogeographic%20analysis%20of%20mormyrids%20indicates%20that%20their%20high%20species%20diversity%20in%20the%20Congo%20Basin%20is%20a%20consequence%20of%20range%20reductions%20of%20previously%20widespread%20ancestors%20and%20that%20the%20highest%20diversity%20of%20craniofacial%20morphologies%20among%20mormyrids%20originated%20in%20this%20basin.%20Special%20emphasis%20on%20a%20taxon-rich%20representation%20for%20mormyrids%20revealed%20pervasive%20misalignment%20between%20our%20phylogenomic%20results%20and%20mormyrid%20taxonomy%20due%20to%20repeated%20instances%20of%20convergence%20for%20extreme%20craniofacial%20morphologies.%20Estimation%20of%20ancestral%20phenotypes%20revealed%20contingent%20evolution%20of%20snout%20elongation%20and%20unique%20projections%20from%20the%20lower%20jaw%20to%20form%20the%20distinctive%20Schnauzenorgan.%20Synthesis%20of%20comparative%20analyses%20suggests%20that%20the%20remarkable%20craniofacial%20morphologies%20of%20mormyrids%20evolved%20convergently%20due%20to%20niche%20partitioning%2C%20likely%20enabled%20by%20interactions%20between%20their%20exclusive%20morphological%20and%20electrosensory%20adaptations.%20%5BAfrica%3B%20ancestral%20state%20estimation%3B%20diversity%3B%20exon%20capture%3B%20freshwater%20fishes%3B%20Phylogenomics.%5D%22%2C%22date%22%3A%22Aug%2010%202022%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%2210.1093%5C%2Fsysbio%5C%2Fsyac001%22%2C%22ISSN%22%3A%221063-5157%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22BTBUS4GS%22%2C%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A32Z%22%7D%7D%2C%7B%22key%22%3A%22SK633J8Z%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Troyer%20et%20al.%22%2C%22parsedDate%22%3A%222022-07-19%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ETroyer%2C%20E.%20M.%2C%20Betancur-R%2C%20R.%2C%20Hughes%2C%20L.%20C.%2C%20Westneat%2C%20M.%2C%20Carnevale%2C%20G.%2C%20White%2C%20W.%20T.%2C%20Pogonoski%2C%20J.%20J.%2C%20Tyler%2C%20J.%20C.%2C%20Baldwin%2C%20C.%20C.%2C%20Ort%26%23xED%3B%2C%20G.%2C%20Brinkworth%2C%20A.%2C%20Clavel%2C%20J.%2C%20%26amp%3B%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%20%282022%29.%20The%20impact%20of%20paleoclimatic%20changes%20on%20body%20size%20evolution%20in%20marine%20fishes.%20%3Ci%3EProceedings%20of%20the%20National%20Academy%20of%20Sciences%20of%20the%20United%20States%20of%20America%3C%5C%2Fi%3E%2C%20%3Ci%3E119%3C%5C%2Fi%3E%2829%29.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2FARTN%20e2122486119%2010.1073%5C%2Fpnas.2122486119%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2FARTN%20e2122486119%2010.1073%5C%2Fpnas.2122486119%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20impact%20of%20paleoclimatic%20changes%20on%20body%20size%20evolution%20in%20marine%20fishes%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22E.%20M.%22%2C%22lastName%22%3A%22Troyer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Betancur-R%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22L.%20C.%22%2C%22lastName%22%3A%22Hughes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Westneat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Carnevale%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%20T.%22%2C%22lastName%22%3A%22White%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20J.%22%2C%22lastName%22%3A%22Pogonoski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20C.%22%2C%22lastName%22%3A%22Tyler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%20C.%22%2C%22lastName%22%3A%22Baldwin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Ort%5Cu00ed%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Brinkworth%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%22%2C%22lastName%22%3A%22Clavel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Arcila%22%7D%5D%2C%22abstractNote%22%3A%22Body%20size%20is%20an%20important%20species%20trait%2C%20correlating%20with%20life%20span%2C%20fecundity%2C%20and%20other%20ecological%20factors.%20Over%20Earth%27s%20geological%20history%2C%20climate%20shifts%20have%20occurred%2C%20potentially%20shaping%20body%20size%20evolution%20in%20many%20clades.%20General%20rules%20attempting%20to%20summarize%20body%20size%20evolution%20include%20Bergmann%27s%20rule%2C%20which%20states%20that%20species%20reach%20larger%20sizes%20in%20cooler%20environments%20and%20smaller%20sizes%20in%20warmer%20environments%2C%20and%20Cope%27s%20rule%2C%20which%20poses%20that%20lineages%20tend%20to%20increase%20in%20size%20over%20evolutionary%20time.%20Tetraodontiform%20fishes%20%28including%20pufferfishes%2C%20boxfishes%2C%20and%20ocean%20sunfishes%29%20provide%20an%20extraordinary%20clade%20to%20test%20these%20rules%20in%20ectotherms%20owing%20to%20their%20exemplary%20fossil%20record%20and%20the%20great%20disparity%20in%20body%20size%20observed%20among%20extant%20and%20fossil%20species.%20We%20examined%20Bergmann%27s%20and%20Cope%27s%20rules%20in%20this%20group%20by%20combining%20phylogenomic%20data%20%281%2C103%20exon%20loci%20from%20185%20extant%20species%29%20with%20210%20anatomical%20characters%20coded%20from%20both%20fossil%20and%20extant%20species.%20We%20aggregated%20data%20layers%20on%20paleoclimate%20and%20body%20size%20from%20the%20species%20examined%2C%20and%20inferred%20a%20set%20of%20time-calibrated%20phylogenies%20using%20tip-dating%20approaches%20for%20downstream%20comparative%20analyses%20of%20body%20size%20evolution%20by%20implementing%20models%20that%20incorporate%20paleoclimatic%20information.%20We%20found%20strong%20support%20for%20a%20temperature-driven%20model%20in%20which%20increasing%20body%20size%20over%20time%20is%20correlated%20with%20decreasing%20oceanic%20temperatures.%20On%20average%2C%20extant%20tetraodontiforms%20are%20two%20to%20three%20times%20larger%20than%20their%20fossil%20counterparts%2C%20which%20otherwise%20evolved%20during%20periods%20of%20warmer%20ocean%20temperatures.%20These%20results%20provide%20strong%20support%20for%20both%20Bergmann%27s%20and%20Cope%27s%20rules%2C%20trends%20that%20are%20less%20studied%20in%20marine%20fishes%20compared%20to%20terrestrial%20vertebrates%20and%20marine%20invertebrates.%22%2C%22date%22%3A%22Jul%2019%202022%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%22ARTN%20e2122486119%2010.1073%5C%2Fpnas.2122486119%22%2C%22ISSN%22%3A%220027-8424%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22BTBUS4GS%22%2C%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A32Z%22%7D%7D%2C%7B%22key%22%3A%22FD83S54L%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Bri%5Cu00f1occoli%20et%20al.%22%2C%22parsedDate%22%3A%222022-03-31%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBri%26%23xF1%3Boccoli%2C%20Y.%20F.%2C%20Bogan%2C%20S.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20Rosso%2C%20J.%20J.%2C%20Mabraga%26%23xF1%3Ba%2C%20E.%2C%20Delpiani%2C%20S.%20M.%2C%20de%20Astarloa%2C%20J.%20M.%20D.%2C%20%26amp%3B%20Cardoso%2C%20Y.%20P.%20%282022%29.%20Molecular%20and%20morphological%20evidence%20revalidates%20Acrobrycon%20tarijae%20%28Characiformes%2C%20Characidae%29%20and%20shows%20hidden%20diversity.%20%3Ci%3EZookeys%3C%5C%2Fi%3E%2C%20%3Ci%3E1091%3C%5C%2Fi%3E%2C%2099%26%23x2013%3B117.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3897%5C%2Fzookeys.1091.73446%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3897%5C%2Fzookeys.1091.73446%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Molecular%20and%20morphological%20evidence%20revalidates%20Acrobrycon%20tarijae%20%28Characiformes%2C%20Characidae%29%20and%20shows%20hidden%20diversity%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Y.%20F.%22%2C%22lastName%22%3A%22Bri%5Cu00f1occoli%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S.%22%2C%22lastName%22%3A%22Bogan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20J.%22%2C%22lastName%22%3A%22Rosso%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22E.%22%2C%22lastName%22%3A%22Mabraga%5Cu00f1a%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S.%20M.%22%2C%22lastName%22%3A%22Delpiani%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20M.%20D.%22%2C%22lastName%22%3A%22de%20Astarloa%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Y.%20P.%22%2C%22lastName%22%3A%22Cardoso%22%7D%5D%2C%22abstractNote%22%3A%22We%20conducted%20a%20revision%20of%20the%20Neotropical%20genus%20Acrobrycon.%20A%20previous%20study%20synonymized%20the%20species%2C%20A.%20ipanquianus%2C%20distributed%20from%20the%20western%20portion%20of%20the%20Amazon%20River%20to%20the%20north-western%20region%20of%20the%20La%20Plata%20River%20Basin%2C%20and%20A.%20tarijae%2C%20with%20type%20locality%20in%20the%20Lipeo%20River%20in%20Bolivia.%20We%20revisited%20this%20result%20by%20collecting%20new%20morphometric%2C%20meristic%2C%20and%20genetic%20data%20%28COI%20mitochondrial%20gene%29%20for%2024%20individuals%20distributed%20along%20La%20Plata%20River%20Basin%20in%20Argentina%2C%20and%20discussed%20our%20results%20in%20the%20context%20of%20multiple%20biogeographic%20processes%20of%20isolation%20in%20that%20basin.%20Our%20results%20revealed%20a%20more%20complex%20history%20of%20diversification%20and%20geographic%20distribution%20across%20Acrobrycon%20species%20than%20previously%20suspected%2C%20probably%20associated%20with%20multiple%20biogeographic%20processes%20of%20isolation%20in%20La%20Plata%20River%20Basin.%20We%20present%20new%20evidence%20that%20led%20us%20to%20reconsider%20the%20validity%20of%20A.%20tarijae%2C%20which%20is%20distinguishable%20from%20A.%20ipanquianus%20by%20the%20number%20of%20vertebrae%20%2837-39%20vs.%2041-42%29%20and%20pleural%20ribs%20%2812-13%20vs.%2014%29.%20These%20results%20were%20also%20supported%20by%20our%20molecular%20analyses%20that%20revealed%20a%20genetic%20divergence%20%3E4%25%20between%20A.%20ipanquianus%20and%20A.%20tarijae.%20We%20also%20identified%20two%20main%20genetic%20clusters%20within%20A.%20tarijae%3A%20the%20first%20cluster%20consisted%20of%20specimens%20from%20the%20Bermejo%2C%20Pilcomayo%2C%20Itiyuro%20and%20Juramento%20river%20basins%20%28northern%20Argentina%29%3B%20and%20the%20second%20cluster%20included%20specimens%20from%20the%20southernmost%20basins%2C%20such%20as%20the%20Sall%20River%20in%20Tucuman%2C%20Cuarto%20River%20in%20the%20province%20of%20Cordoba%20and%20the%20Quinto%20River%20in%20the%20province%20of%20San%20Luis.%20Our%20results%20suggest%20that%20the%20genetic%20structure%20observed%20in%20A.%20tarijae%20is%20the%20result%20of%20the%20type%20of%20drainage%20%28endorheic%20vs.%20exorheic%29%20and%20geographical%20distance.%22%2C%22date%22%3A%22Mar%2031%202022%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%2210.3897%5C%2Fzookeys.1091.73446%22%2C%22ISSN%22%3A%221313-2989%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2276CNVERS%22%5D%2C%22dateModified%22%3A%222025-03-27T23%3A28%3A56Z%22%7D%7D%2C%7B%22key%22%3A%22XL44NWSW%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Arcila%20and%20Orti%22%2C%22parsedDate%22%3A%222022%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3E%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20%26amp%3B%20Orti%2C%20G.%20%282022%29.%20Phylogenetic%20Systematics%20of%20Fishes.%20In%20S.%20Midway%2C%20C.%20Hasler%2C%20%26amp%3B%20P.%20Chakrabarty%20%28Eds.%29%2C%20%3Ci%3EMethods%20for%20Fish%20Biology%2C%202nd%20edition%3C%5C%2Fi%3E%20%282nd%20ed.%29.%20American%20Fisheries%20Society.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22bookSection%22%2C%22title%22%3A%22Phylogenetic%20Systematics%20of%20Fishes%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dahiana%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Guillermo%22%2C%22lastName%22%3A%22Orti%22%7D%2C%7B%22creatorType%22%3A%22editor%22%2C%22firstName%22%3A%22Stephen%22%2C%22lastName%22%3A%22Midway%22%7D%2C%7B%22creatorType%22%3A%22editor%22%2C%22firstName%22%3A%22Caleb%22%2C%22lastName%22%3A%22Hasler%22%7D%2C%7B%22creatorType%22%3A%22editor%22%2C%22firstName%22%3A%22Prosanta%22%2C%22lastName%22%3A%22Chakrabarty%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22bookTitle%22%3A%22Methods%20for%20Fish%20Biology%2C%202nd%20edition%22%2C%22date%22%3A%222022%22%2C%22language%22%3A%22%22%2C%22ISBN%22%3A%22978-1-934874-61-5%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A32Z%22%7D%7D%2C%7B%22key%22%3A%22S9TVDRP5%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Santaquiteria%20et%20al.%22%2C%22parsedDate%22%3A%222021-11%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESantaquiteria%2C%20A.%2C%20Siqueira%2C%20A.%20C.%2C%20Duarte-Ribeiro%2C%20E.%2C%20Carnevale%2C%20G.%2C%20White%2C%20W.%20T.%2C%20Pogonoski%2C%20J.%20J.%2C%20Baldwin%2C%20C.%20C.%2C%20Ort%26%23xED%3B%2C%20G.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20%26amp%3B%20Betancur-R%2C%20R.%20%282021%29.%20Phylogenomics%20and%20Historical%20Biogeography%20of%20Seahorses%2C%20Dragonets%2C%20Goatfishes%2C%20and%20Allies%20%28Teleostei%3A%20Syngnatharia%29%3A%20Assessing%20Factors%20Driving%20Uncertainty%20in%20Biogeographic%20Inferences.%20%3Ci%3ESystematic%20Biology%3C%5C%2Fi%3E%2C%20%3Ci%3E70%3C%5C%2Fi%3E%286%29%2C%201145%26%23x2013%3B1162.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fsysbio%5C%2Fsyab028%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fsysbio%5C%2Fsyab028%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Phylogenomics%20and%20Historical%20Biogeography%20of%20Seahorses%2C%20Dragonets%2C%20Goatfishes%2C%20and%20Allies%20%28Teleostei%3A%20Syngnatharia%29%3A%20Assessing%20Factors%20Driving%20Uncertainty%20in%20Biogeographic%20Inferences%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Santaquiteria%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%20C.%22%2C%22lastName%22%3A%22Siqueira%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22E.%22%2C%22lastName%22%3A%22Duarte-Ribeiro%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Carnevale%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%20T.%22%2C%22lastName%22%3A%22White%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20J.%22%2C%22lastName%22%3A%22Pogonoski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%20C.%22%2C%22lastName%22%3A%22Baldwin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Ort%5Cu00ed%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Betancur-R%22%7D%5D%2C%22abstractNote%22%3A%22The%20charismatic%20trumpetfishes%2C%20goatfishes%2C%20dragonets%2C%20flying%20gurnards%2C%20seahorses%2C%20and%20pipefishes%20encompass%20a%20recently%20defined%20yet%20extraordinarily%20diverse%20Glade%20of%20percomorph%20fishes-the%20series%20Syngnatharia.%20This%20group%20is%20widely%20distributed%20in%20tropical%20and%20warm-temperate%20regions%2C%20with%20a%20great%20proportion%20of%20its%20extant%20diversity%20occurring%20in%20the%20Indo-Pacific.%20Because%20most%20syngnatharians%20feature%20long-range%20dispersal%20capabilities%2C%20tracing%20their%20biogeographic%20origins%20is%20challenging.%20Here%2C%20we%20applied%20an%20integrative%20phylogenomic%20approach%20to%20elucidate%20the%20evolutionary%20biogeography%20of%20syngnatharians.%20We%20built%20upon%20a%20recently%20published%20phylogenomic%20study%20that%20examined%20ultraconserved%20elements%20by%20adding%2062%20species%20%28total%20169%20species%29%20and%20one%20family%20%28Draconettidae%29%2C%20to%20cover%20ca.%2025%25%20of%20the%20species%20diversity%20and%20all%2010%20families%20in%20the%20group.%20We%20inferred%20a%20set%20of%20time-calibrated%20trees%20and%20conducted%20ancestral%20range%20estimations.%20We%20also%20examined%20the%20sensitivity%20of%20these%20analyses%20to%20phylogenetic%20uncertainty%20%28estimated%20from%20multiple%20genomic%20subsets%29%2C%20area%20delimitation%2C%20and%20biogeographic%20models%20that%20include%20or%20exclude%20the%20jump-dispersal%20parameter%20%28j%29.%20Of%20the%20three%20factors%20examined%2C%20we%20found%20that%20the%20j%20parameter%20has%20the%20strongest%20effect%20in%20ancestral%20range%20estimates%2C%20followed%20by%20number%20of%20areas%20defined%2C%20and%20tree%20topology%20and%20divergence%20times.%20After%20accounting%20for%20these%20uncertainties%2C%20our%20results%20reveal%20that%20syngnatharians%20originated%20in%20the%20ancient%20Tethys%20Sea%20ca.%2087%20Ma%20%2884-94%20Ma%3B%20Late%20Cretaceous%29%20and%20subsequently%20occupied%20the%20Indo-Pacific.%20Throughout%20syngnatharian%20history%2C%20multiple%20independent%20lineages%20colonized%20the%20eastern%20Pacific%20%286-8%20times%29%20and%20the%20Atlantic%20%286-14%20times%29%20from%20their%20center%20of%20origin%2C%20with%20most%20events%20taking%20place%20following%20an%20east-to-west%20route%20prior%20to%20the%20closure%20of%20the%20Tethys%20Seaway%20ca.%2012-18%20Ma.%20Ultimately%2C%20our%20study%20highlights%20the%20importance%20of%20accounting%20for%20different%20factors%20generating%20uncertainty%20in%20macroevolutionary%20and%20biogeographic%20inferences.%22%2C%22date%22%3A%22Nov%202021%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%2210.1093%5C%2Fsysbio%5C%2Fsyab028%22%2C%22ISSN%22%3A%221063-5157%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22BTBUS4GS%22%2C%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A32Z%22%7D%7D%2C%7B%22key%22%3A%22QFQJCIZT%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Arcila%20et%20al.%22%2C%22parsedDate%22%3A%222021-11%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3E%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20Hughes%2C%20L.%20C.%2C%20Mel%26%23xE9%3Bndez-Vazquez%2C%20B.%2C%20Baldwin%2C%20C.%20C.%2C%20White%2C%20W.%20T.%2C%20Carpenter%2C%20K.%20E.%2C%20Williams%2C%20J.%20T.%2C%20Santos%2C%20M.%20D.%2C%20Pogonoski%2C%20J.%20J.%2C%20Miya%2C%20M.%2C%20Ort%26%23xED%3B%2C%20G.%2C%20%26amp%3B%20Betancur-R%2C%20R.%20%282021%29.%20Testing%20the%20Utility%20of%20Alternative%20Metrics%20of%20Branch%20Support%20to%20Address%20the%20Ancient%20Evolutionary%20Radiation%20of%20Tunas%2C%20Stromateoids%2C%20and%20Allies%20%28Teleostei%3A%20Pelagiaria%29.%20%3Ci%3ESystematic%20Biology%3C%5C%2Fi%3E%2C%20%3Ci%3E70%3C%5C%2Fi%3E%286%29%2C%201123%26%23x2013%3B1144.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fsysbio%5C%2Fsyab018%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fsysbio%5C%2Fsyab018%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Testing%20the%20Utility%20of%20Alternative%20Metrics%20of%20Branch%20Support%20to%20Address%20the%20Ancient%20Evolutionary%20Radiation%20of%20Tunas%2C%20Stromateoids%2C%20and%20Allies%20%28Teleostei%3A%20Pelagiaria%29%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22L.%20C.%22%2C%22lastName%22%3A%22Hughes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22B.%22%2C%22lastName%22%3A%22Mel%5Cu00e9ndez-Vazquez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%20C.%22%2C%22lastName%22%3A%22Baldwin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%20T.%22%2C%22lastName%22%3A%22White%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22K.%20E.%22%2C%22lastName%22%3A%22Carpenter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20T.%22%2C%22lastName%22%3A%22Williams%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%20D.%22%2C%22lastName%22%3A%22Santos%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20J.%22%2C%22lastName%22%3A%22Pogonoski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Miya%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Ort%5Cu00ed%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Betancur-R%22%7D%5D%2C%22abstractNote%22%3A%22The%20use%20of%20high-throughput%20sequencing%20technologies%20to%20produce%20genome-scale%20data%20sets%20was%20expected%20to%20settle%20some%20long-standing%20controversies%20across%20the%20Tree%20of%20Life%2C%20particularly%20in%20areas%20where%20short%20branches%20occur%20at%20deep%20timescales.%20Instead%2C%20these%20data%20sets%20have%20often%20yielded%20many%20well-supported%20but%20conflicting%20topologies%2C%20and%20highly%20variable%20genetree%20distributions.%20A%20variety%20of%20branch-support%20metrics%20beyond%20the%20nonparametric%20bootstrap%20are%20now%20available%20to%20assess%20how%20robust%20a%20phylogenetic%20hypothesis%20may%20be%2C%20as%20well%20as%20new%20methods%20to%20quantify%20gene-tree%20discordance.%20We%20applied%20multiple%20branch-support%20metrics%20to%20a%20study%20of%20an%20ancient%20group%20of%20marine%20fishes%20%28Teleostei%3A%20Pelagiaria%29%20whose%20interfamilial%20relationships%20have%20proven%20difficult%20to%20resolve%20due%20to%20a%20rapid%20accumulation%20of%20lineages%20very%20early%20in%20its%20history.%20We%20analyzed%20hundreds%20of%20loci%20including%20published%20ultraconserved%20elements%20and%20newly%20generated%20exonic%20data%20along%20with%20their%20flanking%20regions%20to%20represent%20all%2016%20extant%20families%20for%20more%20than%20150%20out%20of%20284%20valid%20species%20in%20the%20group.%20Branch%20support%20was%20typically%20lower%20at%20inter-%20than%20intra-familial%20relationships%20regardless%20of%20the%20type%20of%20marker%20used.%20Several%20nodes%20that%20were%20highly%20supported%20with%20bootstrap%20had%20a%20very%20low%20site%20and%20gene-tree%20concordance%2C%20revealing%20underlying%20conflict.%20Despite%20this%20conflict%2C%20we%20were%20able%20to%20identify%20four%20consistent%20interfamilial%20clades%2C%20each%20comprised%20of%20two%20or%20three%20families.%20Combining%20exons%20with%20their%20flanking%20regions%20also%20produced%20increased%20branch%20lengths%20at%20the%20deep%20branches%20of%20the%20pelagiarian%20tree.%20Our%20results%20demonstrate%20the%20limitations%20of%20employing%20current%20metrics%20of%20branch%20support%20and%20species-tree%20estimation%20when%20assessing%20the%20confidence%20of%20ancient%20evolutionary%20radiations%20and%20emphasize%20the%20necessity%20to%20embrace%20alternative%20measurements%20to%20explore%20phylogenetic%20uncertainty%20and%20discordance%20in%20phylogenomic%20data%20sets.%22%2C%22date%22%3A%22Nov%202021%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%2210.1093%5C%2Fsysbio%5C%2Fsyab018%22%2C%22ISSN%22%3A%221063-5157%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22BTBUS4GS%22%2C%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A32Z%22%7D%7D%2C%7B%22key%22%3A%22DGUHNGDU%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Atta%20et%20al.%22%2C%22parsedDate%22%3A%222021%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EAtta%2C%20C.%20J.%2C%20Yuan%2C%20H.%2C%20Li%2C%20C.%20H.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20Betancur-R%2C%20R.%2C%20Hughes%2C%20L.%20C.%2C%20Ort%26%23xED%3B%2C%20G.%2C%20%26amp%3B%20Tornabene%2C%20L.%20%282021%29.%20Exon-capture%20data%20and%20locus%20screening%20provide%20new%20insights%20into%20the%20phylogeny%20of%20flatfishes%20%28Pleuronectoidei%29.%20%3Ci%3EMolecular%20Phylogenetics%20and%20Evolution%3C%5C%2Fi%3E%2C%20%3Ci%3E166%3C%5C%2Fi%3E.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2Fhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.ympev.2021.107315%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2Fhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.ympev.2021.107315%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Exon-capture%20data%20and%20locus%20screening%20provide%20new%20insights%20into%20the%20phylogeny%20of%20flatfishes%20%28Pleuronectoidei%29%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%20J.%22%2C%22lastName%22%3A%22Atta%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22H.%22%2C%22lastName%22%3A%22Yuan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%20H.%22%2C%22lastName%22%3A%22Li%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Betancur-R%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22L.%20C.%22%2C%22lastName%22%3A%22Hughes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Ort%5Cu00ed%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22L.%22%2C%22lastName%22%3A%22Tornabene%22%7D%5D%2C%22abstractNote%22%3A%22There%20is%20an%20extensive%20collection%20of%20literature%20on%20the%20taxonomy%20and%20phylogenetics%20of%20flatfishes%20%28Pleuronectiformes%29%20that%20extends%20over%20two%20centuries%2C%20but%20consensus%20on%20many%20of%20their%20evolutionary%20relationships%20remains%20elusive.%20Phylogenetic%20uncertainty%20stems%20from%20highly%20divergent%20results%20derived%20from%20morphological%20and%20genetic%20characters%2C%20and%20between%20various%20molecular%20datasets.%20Deciphering%20relationships%20is%20complicated%20by%20rapid%20diversification%20early%20in%20the%20Pleuronectiformes%20tree%20and%20an%20abundance%20of%20studies%20that%20incompletely%20and%20inconsistently%20sample%20taxa%20and%20genetic%20markers.%20We%20present%20phylogenies%20based%20on%20a%20genome-wide%20dataset%20%284%2C434%20nuclear%20markers%20via%20exoncapture%29%20and%20wide%20taxon%20sampling%20%2886%20species%20spanning%2012%20of%2016%20families%29%20of%20the%20largest%20flatfish%20suborder%20%28Pleuronectoidei%29.%20Nine%20different%20subsets%20of%20the%20data%20and%20two%20tree%20construction%20approaches%20%28eighteen%20phylogenies%20in%20total%29%20are%20remarkably%20consistent%20with%20other%20recent%20molecular%20phylogenies%2C%20and%20show%20strong%20support%20for%20the%20monophyly%20of%20all%20families%20included%20except%20Pleuronectidae.%20Analyses%20resolved%20a%20novel%20phylogenetic%20hypothesis%20for%20the%20family%20Rhombosoleidae%20as%20being%20within%20the%20Pleuronectoidea%20rather%20than%20the%20Soleoidea%2C%20and%20failed%20to%20support%20the%20subfamily%20Hippoglossinae%20as%20a%20monophyletic%20group.%20Our%20results%20were%20corroborated%20with%20evidence%20from%20previous%20phylogenetic%20studies%20to%20outline%20regions%20of%20persistent%20phylogenetic%20uncertainty%20and%20identify%20groups%20in%20need%20of%20further%20phylogenetic%20inference.%22%2C%22date%22%3A%2212%5C%2F2021%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.ympev.2021.107315%22%2C%22ISSN%22%3A%221055-7903%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22BTBUS4GS%22%2C%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-02-27T21%3A25%3A47Z%22%7D%7D%2C%7B%22key%22%3A%22TPBJ6PQV%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Rincon-Sandoval%20et%20al.%22%2C%22parsedDate%22%3A%222020-12%22%2C%22numChildren%22%3A3%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ERincon-Sandoval%2C%20M.%2C%20Duarte-Ribeiro%2C%20E.%2C%20Davis%2C%20A.%20M.%2C%20Santaquiteria%2C%20A.%2C%20Hughes%2C%20L.%20C.%2C%20Baldwin%2C%20C.%20C.%2C%20Soto-Torres%2C%20L.%2C%20Acero%2C%20A.%2C%20Walker%2C%20H.%20J.%2C%20Carpenter%2C%20K.%20E.%2C%20Sheaves%2C%20M.%2C%20Orti%2C%20G.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20%26amp%3B%20Betancur-R%2C%20R.%20%282020%29.%20Evolutionary%20determinism%20and%20convergence%20associated%20with%20water-column%20transitions%20in%20marine%20fishes.%20%3Ci%3EProceedings%20of%20the%20National%20Academy%20of%20Sciences%20of%20the%20United%20States%20of%20America%3C%5C%2Fi%3E%2C%20%3Ci%3E117%3C%5C%2Fi%3E%2852%29%2C%2033396%26%23x2013%3B33403.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1073%5C%2Fpnas.2006511117%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1073%5C%2Fpnas.2006511117%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Evolutionary%20determinism%20and%20convergence%20associated%20with%20water-column%20transitions%20in%20marine%20fishes%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Rincon-Sandoval%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22E.%22%2C%22lastName%22%3A%22Duarte-Ribeiro%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%20M.%22%2C%22lastName%22%3A%22Davis%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Santaquiteria%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22L.%20C.%22%2C%22lastName%22%3A%22Hughes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%20C.%22%2C%22lastName%22%3A%22Baldwin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22L.%22%2C%22lastName%22%3A%22Soto-Torres%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Acero%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22H.%20J.%22%2C%22lastName%22%3A%22Walker%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22K.%20E.%22%2C%22lastName%22%3A%22Carpenter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Sheaves%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Orti%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Betancur-R%22%7D%5D%2C%22abstractNote%22%3A%22Repeatable%2C%20convergent%20outcomes%20are%20prima%20facie%20evidence%20for%20determinism%20in%20evolutionary%20processes.%20Among%20fishes%2C%20well-known%20examples%20include%20microevolutionary%20habitat%20transitions%20into%20the%20water%20column%2C%20where%20freshwater%20populations%20%28e.g.%2C%20sticklebacks%2C%20cichlids%2C%20and%20whitefishes%29%20recurrently%20diverge%20toward%20slender-bodied%20pelagic%20forms%20and%20deep-bodied%20benthic%20forms.%20However%2C%20the%20consequences%20of%20such%20processes%20at%20deeper%20macroevolutionary%20scales%20in%20the%20marine%20environment%20are%20less%20clear.%20We%20applied%20a%20phylogenomics-based%20integrative%2C%20comparative%20approach%20to%20test%20hypotheses%20about%20the%20scope%20and%20strength%20of%20convergence%20in%20a%20marine%20fish%20clade%20with%20a%20worldwide%20distribution%20%28snappers%20and%20fusiliers%2C%20family%20Lutjanidae%29%20featuring%20multiple%20water-column%20transitions%20over%20the%20past%2045%20million%20years.%20We%20collected%20genome-wide%20exon%20data%20for%20110%20%28similar%20to%2080%25%29%20species%20in%20the%20group%20and%20aggregated%20data%20layers%20for%20body%20shape%2C%20habitat%20occupancy%2C%20geographic%20distribution%2C%20and%20paleontological%20and%20geological%20information.%20We%20also%20implemented%20approaches%20using%20genomic%20subsets%20to%20account%20for%20phylogenetic%20uncertainty%20in%20comparative%20analyses.%20Our%20results%20show%20independent%20incursions%20into%20the%20water%20column%20by%20ancestral%20benthic%20lineages%20in%20all%20major%20oceanic%20basins.%20These%20evolutionary%20transitions%20are%20persistently%20associated%20with%20convergent%20phenotypes%2C%20where%20deep-bodied%20benthic%20forms%20with%20truncate%20caudal%20fins%20repeatedly%20evolve%20into%20slender%20midwater%20species%20with%20furcate%20caudal%20fins.%20Lineage%20diversification%20and%20transition%20dynamics%20vary%20asymmetrically%20between%20habitats%2C%20with%20benthic%20lineages%20diversifying%20faster%20and%20colonizing%20midwater%20habitats%20more%20often%20than%20the%20reverse.%20Convergent%20ecological%20and%20functional%20phenotypes%20along%20the%20benthic-pelagic%20axis%20are%20pervasive%20among%20different%20lineages%20and%20across%20vastly%20different%20evolutionary%20scales%2C%20achieving%20predictable%20high-fitness%20solutions%20for%20similar%20environmental%20challenges%2C%20ultimately%20demonstrating%20strong%20determinism%20in%20fish%20body-shape%20evolution.%22%2C%22date%22%3A%222020%5C%2F12%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1073%5C%2Fpnas.2006511117%22%2C%22ISSN%22%3A%220027-8424%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22BTBUS4GS%22%2C%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A32Z%22%7D%7D%2C%7B%22key%22%3A%22XAVZGVTD%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Hughes%20et%20al.%22%2C%22parsedDate%22%3A%222020-10%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EHughes%2C%20L.%20C.%2C%20Ort%26%23xED%3B%2C%20G.%2C%20Saad%2C%20H.%2C%20Li%2C%20C.%20H.%2C%20White%2C%20W.%20T.%2C%20Baldwin%2C%20C.%20C.%2C%20Crandall%2C%20K.%20A.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20%26amp%3B%20Betancur%2C%20R.%20%282020%29.%20Exon%20probe%20sets%20and%20bioinformatics%20pipelines%20for%20all%20levels%20of%20fish%20phylogenomics.%20%3Ci%3EMol%20Ecol%20Resour%3C%5C%2Fi%3E%2C%20%3Ci%3E21%3C%5C%2Fi%3E%283%29%2C%20816%26%23x2013%3B833.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2F1755-0998.13287%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2F1755-0998.13287%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Exon%20probe%20sets%20and%20bioinformatics%20pipelines%20for%20all%20levels%20of%20fish%20phylogenomics%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22L.%20C.%22%2C%22lastName%22%3A%22Hughes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Ort%5Cu00ed%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22H.%22%2C%22lastName%22%3A%22Saad%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%20H.%22%2C%22lastName%22%3A%22Li%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%20T.%22%2C%22lastName%22%3A%22White%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%20C.%22%2C%22lastName%22%3A%22Baldwin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22K.%20A.%22%2C%22lastName%22%3A%22Crandall%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Betancur%22%7D%5D%2C%22abstractNote%22%3A%22Exon%20markers%20have%20a%20long%20history%20of%20use%20in%20phylogenetics%20of%20ray-finned%20fishes%2C%20the%20most%20diverse%20clade%20of%20vertebrates%20with%20more%20than%2035%2C000%20species.%20As%20the%20number%20of%20published%20genomes%20increases%2C%20it%20has%20become%20easier%20to%20test%20exons%20and%20other%20genetic%20markers%20for%20signals%20of%20ancient%20duplication%20events%20and%20filter%20out%20paralogues%20that%20can%20mislead%20phylogenetic%20analysis.%20We%20present%20seven%20new%20probe%20sets%20for%20current%20target-capture%20phylogenomic%20protocols%20that%20capture%201%2C104%20exons%20explicitly%20filtered%20for%20paralogues%20using%20gene%20trees.%20These%20seven%20probe%20sets%20span%20the%20diversity%20of%20teleost%20fishes%2C%20including%20four%20sets%20that%20target%20five%20hyperdiverse%20percomorph%20clades%20which%20together%20comprise%20ca.%2017%2C000%20species%20%28Carangaria%2C%20Ovalentaria%2C%20Eupercaria%2C%20and%20Syngnatharia%20%2B%20Pelagiaria%20combined%29.%20We%20additionally%20included%20probes%20to%20capture%20legacy%20nuclear%20exons%20and%20mitochondrial%20markers%20that%20have%20been%20commonly%20used%20in%20fish%20phylogenetics%20%28despite%20some%20exons%20being%20flagged%20for%20paralogues%29%20to%20facilitate%20integration%20of%20old%20and%20new%20molecular%20phylogenetic%20matrices.%20We%20tested%20these%20probes%20experimentally%20for%2056%20fish%20species%20%28eight%20species%20per%20probe%20set%29%20and%20merged%20new%20exon-capture%20sequence%20data%20into%20an%20existing%20data%20matrix%20of%201%2C104%20exons%20and%20300%20ray-finned%20fish%20species.%20We%20provide%20an%20optimized%20bioinformatics%20pipeline%20to%20assemble%20exon%20capture%20data%20from%20raw%20reads%20to%20alignments%20for%20downstream%20analysis.%20We%20show%20that%20legacy%20loci%20with%20known%20paralogues%20are%20at%20risk%20of%20assembling%20duplicated%20sequences%20with%20target-capture%2C%20but%20we%20also%20assembled%20many%20useful%20orthologous%20sequences%20that%20can%20be%20integrated%20with%20many%20PCR-generated%20matrices.%20These%20probe%20sets%20are%20a%20valuable%20resource%20for%20advancing%20fish%20phylogenomics%20because%20targeted%20exons%20can%20easily%20be%20extracted%20from%20increasingly%20available%20whole%20genome%20and%20transcriptome%20data%20sets%2C%20and%20also%20may%20be%20integrated%20with%20existing%20PCR-based%20exon%20and%20mitochondrial%20data.%22%2C%22date%22%3A%22Oct.%202020%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%2210.1111%5C%2F1755-0998.13287%22%2C%22ISSN%22%3A%221755-098x%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22BTBUS4GS%22%2C%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-02-27T17%3A23%3A11Z%22%7D%7D%2C%7B%22key%22%3A%22LGYMCUUP%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kolmann%20et%20al.%22%2C%22parsedDate%22%3A%222020-08%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKolmann%2C%20M.%20A.%2C%20Hughes%2C%20L.%20C.%2C%20Hernandez%2C%20L.%20P.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20Betancur-R%2C%20R.%2C%20Sabaj%2C%20M.%20H.%2C%20L%26%23xF3%3Bpez-Fern%26%23xE1%3Bndez%2C%20H.%2C%20%26amp%3B%20Ort%26%23xED%3B%2C%20G.%20%282020%29.%20Phylogenomics%20of%20Piranhas%20and%20Pacus%20%28Serrasalmidae%29%20Uncovers%20How%20Dietary%20Convergence%20and%20Parallelism%20Obfuscate%20Traditional%20Morphological%20Taxonomy.%20%3Ci%3ESystematic%20Biology%3C%5C%2Fi%3E%2C%20%3Ci%3E70%3C%5C%2Fi%3E%283%29%2C%20576%26%23x2013%3B592.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fsysbio%5C%2Fsyaa065%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fsysbio%5C%2Fsyaa065%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Phylogenomics%20of%20Piranhas%20and%20Pacus%20%28Serrasalmidae%29%20Uncovers%20How%20Dietary%20Convergence%20and%20Parallelism%20Obfuscate%20Traditional%20Morphological%20Taxonomy%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%20A.%22%2C%22lastName%22%3A%22Kolmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22L.%20C.%22%2C%22lastName%22%3A%22Hughes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22L.%20P.%22%2C%22lastName%22%3A%22Hernandez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Betancur-R%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%20H.%22%2C%22lastName%22%3A%22Sabaj%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22H.%22%2C%22lastName%22%3A%22L%5Cu00f3pez-Fern%5Cu00e1ndez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Ort%5Cu00ed%22%7D%5D%2C%22abstractNote%22%3A%22The%20Amazon%20and%20neighboring%20South%20American%20river%20basins%20harbor%20the%20world%27s%20most%20diverse%20assemblages%20of%20freshwater%20fishes.%20One%20of%20the%20most%20prominent%20South%20American%20fish%20families%20is%20the%20Serrasalmidae%20%28pacus%20and%20piranhas%29%2C%20found%20in%20nearly%20every%20continental%20basin.%20Serrasalmids%20are%20keystone%20ecological%20taxa%2C%20being%20some%20of%20the%20top%20riverine%20predators%20as%20well%20as%20the%20primary%20seed%20dispersers%20in%20the%20flooded%20forest.%20Despite%20their%20widespread%20occurrence%20and%20notable%20ecologies%2C%20serrasalmid%20evolutionary%20history%20and%20systematics%20are%20controversial.%20For%20example%2C%20the%20sister%20taxon%20to%20serrasalmids%20is%20contentious%2C%20the%20relationships%20of%20major%20clades%20within%20the%20family%20are%20inconsistent%20across%20different%20methodologies%2C%20and%20half%20of%20the%20extant%20serrasalmid%20genera%20are%20suggested%20to%20be%20non-monophyletic.%20We%20analyzed%20exon%20capture%20to%20reexamine%20the%20evolutionary%20relationships%20among%2063%20%28of%2099%29%20species%20across%20all%2016%20serrasalmid%20genera%20and%20their%20nearest%20outgroups%2C%20including%20multiple%20individuals%20per%20species%20to%20account%20for%20cryptic%20lineages.%20To%20reconstruct%20the%20timeline%20of%20serrasalmid%20diversification%2C%20we%20time-calibrated%20this%20phylogeny%20using%20two%20different%20fossil-calibration%20schemes%20to%20account%20for%20uncertainty%20in%20taxonomy%20with%20respect%20to%20fossil%20teeth.%20Finally%2C%20we%20analyzed%20diet%20evolution%20across%20the%20family%20and%20comment%20on%20associated%20changes%20in%20dentition%2C%20highlighting%20the%20ecomorphological%20diversity%20within%20serrasalmids.%20We%20document%20widespread%20non-monophyly%20of%20genera%20within%20Myleinae%2C%20as%20well%20as%20between%20Serrasalmus%20and%20Pristobrycon%2C%20and%20propose%20that%20reliance%20on%20traits%20like%20teeth%20to%20distinguish%20among%20genera%20is%20confounded%20by%20ecological%20homoplasy%2C%20especially%20among%20herbivorous%20and%20omnivorous%20taxa.%20We%20clarify%20the%20relationships%20among%20all%20serrasalmid%20genera%2C%20propose%20new%20subfamily%20affiliations%2C%20and%20support%20hemiodontids%20as%20the%20sister%20taxon%20to%20Serrasalmidae.%22%2C%22date%22%3A%22August%202020%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%2210.1093%5C%2Fsysbio%5C%2Fsyaa065%22%2C%22ISSN%22%3A%221063-5157%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22BTBUS4GS%22%2C%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-02-27T17%3A24%3A37Z%22%7D%7D%2C%7B%22key%22%3A%22KS6XG4EJ%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Mel%5Cu00e9ndez-Vazquez%20et%20al.%22%2C%22parsedDate%22%3A%222019-12%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EMel%26%23xE9%3Bndez-Vazquez%2C%20F.%2C%20Olmeda-Salda%26%23xF1%3Ba%2C%20M.%2C%20Cruz%2C%20J.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20%26amp%3B%20Betancur%2C%20R.%20%282019%29.%20Effects%20of%20Hurricane%20Maria%20in%20hamlet%20communities%20%28Serranidae%3A%20spp.%29%20in%20Puerto%20Rico.%20%3Ci%3EEcological%20Indicators%3C%5C%2Fi%3E%2C%20%3Ci%3E107%3C%5C%2Fi%3E.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2FARTN%20105591%2010.1016%5C%2Fj.ecolind.2019.105591%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2FARTN%20105591%2010.1016%5C%2Fj.ecolind.2019.105591%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Effects%20of%20Hurricane%20Maria%20in%20hamlet%20communities%20%28Serranidae%3A%20spp.%29%20in%20Puerto%20Rico%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22F.%22%2C%22lastName%22%3A%22Mel%5Cu00e9ndez-Vazquez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Olmeda-Salda%5Cu00f1a%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%22%2C%22lastName%22%3A%22Cruz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Betancur%22%7D%5D%2C%22abstractNote%22%3A%22Hamlets%20%28Hypoplectrus%20spp.%29%20are%20hermaphroditic%2C%20carnivorous%2C%20and%20highly%20territorial%20fishes%20in%20the%20family%20Serranidae%20that%20are%20endemic%20to%20the%20Western%20Atlantic.%20We%20studied%2010%20reefs%20located%20in%20the%20La%20Parguera%20Natural%20Reserve%20in%20Puerto%20Rico%20and%20report%20differences%20in%20hamlet%20communities%20after%20the%20passage%20of%20Hurricane%20Maria.%20Our%20results%20were%20compared%20to%20surveys%20conducted%20in%20the%20years%202000%20and%202017%2C%20before%20the%20reefs%20were%20hit%20by%20Hurricane%20Maria%20in%202017.%20Non-metric%20multidimensional%20analyses%20revealed%20a%20%5C%22boomerang%20pattern%5C%22%20in%20species%20composition%20and%20abundance%2C%20with%20high%20diversity%20in%202000%2C%20low%20diversity%20in%202017%2C%20and%20a%20subsequent%20return%20to%20high%20diversity%20levels%20in%202018.%20By%20and%20large%2C%20the%20study%20reveals%20a%20positive%20effect%20on%20the%20diversity%20of%20hamlet%20communities%20in%20the%20aftermath%20of%20Hurricane%20Maria.%20The%20reemergence%20of%20diversity%20patterns%2C%20including%20the%20recording%20of%20previously%20unobserved%20species%20in%20the%20study%20site%20serves%20as%20indicator%20of%20the%20underlying%20and%20often%20underestimated%20benefits%20of%20major%20disturbance%20events.%22%2C%22date%22%3A%22Dec%202019%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%22ARTN%20105591%2010.1016%5C%2Fj.ecolind.2019.105591%22%2C%22ISSN%22%3A%221470-160x%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22BTBUS4GS%22%2C%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A32Z%22%7D%7D%2C%7B%22key%22%3A%226WZE8A96%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Bemis%20et%20al.%22%2C%22parsedDate%22%3A%222019-04-01%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBemis%2C%20K.%20E.%2C%20Tyler%2C%20J.%20C.%2C%20%26amp%3B%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%20%282019%29.%20Life%20history%2C%20distribution%20and%20molecular%20phylogenetics%20of%20the%20Upward-Mouth%20Spikefish%20Atrophacanthus%20japonicus%20%28Teleostei%3A%20Tetraodontiformes%3A%20Triacanthodidae%29.%20%3Ci%3EJournal%20of%20Fish%20Biology%3C%5C%2Fi%3E%2C%20%3Ci%3E94%3C%5C%2Fi%3E%284%29%2C%20578%26%23x2013%3B584.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjfb.13923%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjfb.13923%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Life%20history%2C%20distribution%20and%20molecular%20phylogenetics%20of%20the%20Upward-Mouth%20Spikefish%20Atrophacanthus%20japonicus%20%28Teleostei%3A%20Tetraodontiformes%3A%20Triacanthodidae%29%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katherine%20E.%22%2C%22lastName%22%3A%22Bemis%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22James%20C.%22%2C%22lastName%22%3A%22Tyler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dahiana%22%2C%22lastName%22%3A%22Arcila%22%7D%5D%2C%22abstractNote%22%3A%22Ninety-six%20juvenile%20specimens%20%2837%3F54%3Fmm%20standard%20length%3B%20LS%29%20of%20the%20rarely%20collected%20Upward-Mouth%20Spikefish%20Atrophacanthus%20japonicus%20%28Triacanthodidae%29%20were%20obtained%20from%20the%20stomachs%20of%20three%20Yellowfin%20Tuna%20Thunnus%20albacares%20collected%20off%20Guam%20in%20the%20Mariana%20Islands%20in%20the%20central%20Pacific%20Ocean.%20These%20specimens%20extend%20the%20range%20of%20A.%20japonicus%20eastward%20into%20Oceania.%20We%20review%20the%20systematic%20characters%20of%20the%20monotypic%20genus%20Atrophacanthus%20and%20present%20colour%20photographs%20of%20freshly%20collected%20specimens.%20The%20diet%20of%20the%20juvenile%20specimens%20of%20A.%20japonicus%20consisted%20of%20thecosome%20pteropods%20and%20foraminiferans.%20We%20present%20a%20range%20map%20of%20A.%20japonicus%20based%20on%20all%20known%20specimens%20and%20show%20that%20specimen%20size%20is%20related%20to%20whether%20specimens%20were%20collected%20in%20the%20pelagic%20zone%20or%20on%20the%20bottom.%20Our%20results%20support%20that%2C%20compared%20to%20all%20other%20Triacanthodidae%2C%20A.%20japonicus%20has%20an%20unusually%20extended%20pelagic%20larval%20and%20juvenile%20period%2C%20up%20to%2054%3Fmm%20LS%2C%20before%20settling%20to%20the%20bottom%20as%20adults.%20Lastly%2C%20we%20provide%20a%20multilocus%20phylogeny%20addressing%20the%20phylogenetic%20placement%20of%20Atrophacanthus%20based%20on%20eight%20of%2011%20triacanthodid%20genera%20and%20six%20genetic%20markers.%20Our%20results%20reveal%20that%20Atrophacanthus%20is%20the%20sister%20group%20of%20Macrorhamphosodes%20and%20they%20provide%20new%20insights%20about%20the%20evolutionary%20history%20of%20the%20family.%22%2C%22date%22%3A%222019%5C%2F04%5C%2F01%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1111%5C%2Fjfb.13923%22%2C%22ISSN%22%3A%220022-1112%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A32Z%22%7D%7D%2C%7B%22key%22%3A%22BHLWPEEN%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Betancur-R%20et%20al.%22%2C%22parsedDate%22%3A%222019-02%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBetancur-R%2C%20R.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20Vari%2C%20R.%20P.%2C%20Hughes%2C%20L.%20C.%2C%20Oliveira%2C%20C.%2C%20Sabaj%2C%20M.%20H.%2C%20%26amp%3B%20Ort%26%23xED%3B%2C%20G.%20%282019%29.%20Phylogenomic%20incongruence%2C%20hypothesis%20testing%2C%20and%20taxonomic%20sampling%3A%20The%20monophyly%20of%20characiform%20fishes.%20%3Ci%3EEvolution%3C%5C%2Fi%3E%2C%20%3Ci%3E73%3C%5C%2Fi%3E%282%29%2C%20329%26%23x2013%3B345.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fevo.13649%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fevo.13649%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Phylogenomic%20incongruence%2C%20hypothesis%20testing%2C%20and%20taxonomic%20sampling%3A%20The%20monophyly%20of%20characiform%20fishes%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Betancur-R%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%20P.%22%2C%22lastName%22%3A%22Vari%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22L.%20C.%22%2C%22lastName%22%3A%22Hughes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%22%2C%22lastName%22%3A%22Oliveira%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%20H.%22%2C%22lastName%22%3A%22Sabaj%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Ort%5Cu00ed%22%7D%5D%2C%22abstractNote%22%3A%22Phylogenomic%20studies%20using%20genome-wide%20datasets%20are%20quickly%20becoming%20the%20state%20of%20the%20art%20for%20systematics%20and%20comparative%20studies%2C%20but%20in%20many%20cases%2C%20they%20result%20in%20strongly%20supported%20incongruent%20results.%20The%20extent%20to%20which%20this%20conflict%20is%20real%20depends%20on%20different%20sources%20of%20error%20potentially%20affecting%20big%20datasets%20%28assembly%2C%20stochastic%2C%20and%20systematic%20error%29.%20Here%2C%20we%20apply%20a%20recently%20developed%20methodology%20%28GGI%20or%20gene%20genealogy%20interrogation%29%20and%20data%20curation%20to%20new%20and%20published%20datasets%20with%20more%20than%201000%20exons%2C%20500%20ultraconserved%20element%20%28UCE%29%20loci%2C%20and%20transcriptomic%20sequences%20that%20support%20incongruent%20hypotheses.%20The%20contentious%20non-monophyly%20of%20the%20order%20Characiformes%20proposed%20by%20two%20studies%20is%20shown%20to%20be%20a%20spurious%20outcome%20induced%20by%20sample%20contamination%20in%20the%20transcriptomic%20dataset%20and%20an%20ambiguous%20result%20due%20to%20poor%20taxonomic%20sampling%20in%20the%20UCE%20dataset.%20By%20exploring%20the%20effects%20of%20number%20of%20taxa%20and%20loci%20used%20for%20analysis%2C%20we%20show%20that%20the%20power%20of%20GGI%20to%20discriminate%20among%20competing%20hypotheses%20is%20diminished%20by%20limited%20taxonomic%20sampling%2C%20but%20not%20equally%20sensitive%20to%20gene%20sampling.%20Taken%20together%2C%20our%20results%20reinforce%20the%20notion%20that%20merely%20increasing%20the%20number%20of%20genetic%20loci%20for%20a%20few%20representative%20taxa%20is%20not%20a%20robust%20strategy%20to%20advance%20phylogenetic%20knowledge%20of%20recalcitrant%20groups.%20We%20leverage%20the%20expanded%20exon%20capture%20dataset%20generated%20here%20for%20Characiformes%20%28206%20species%20in%2023%20out%20of%2024%20families%29%20to%20produce%20a%20comprehensive%20phylogeny%20and%20a%20revised%20classification%20of%20the%20order.%22%2C%22date%22%3A%22Feb%202019%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%2210.1111%5C%2Fevo.13649%22%2C%22ISSN%22%3A%220014-3820%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22BTBUS4GS%22%2C%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A32Z%22%7D%7D%2C%7B%22key%22%3A%229FK92BVB%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Hughes%20et%20al.%22%2C%22parsedDate%22%3A%222018-06-12%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EHughes%2C%20L.%20C.%2C%20Ort%26%23xED%3B%2C%20G.%2C%20Huang%2C%20Y.%2C%20Sun%2C%20Y.%2C%20Baldwin%2C%20C.%20C.%2C%20Thompson%2C%20A.%20W.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20Betancur%2C%20R.%20R.%2C%20Li%2C%20C.%2C%20Becker%2C%20L.%2C%20Bellora%2C%20N.%2C%20Zhao%2C%20X.%2C%20Li%2C%20X.%2C%20Wang%2C%20M.%2C%20Fang%2C%20C.%2C%20Xie%2C%20B.%2C%20Zhou%2C%20Z.%2C%20Huang%2C%20H.%2C%20Chen%2C%20S.%2C%20%26%23x2026%3B%20Shi%2C%20Q.%20%282018%29.%20Comprehensive%20phylogeny%20of%20ray-finned%20fishes%20%28Actinopterygii%29%20based%20on%20transcriptomic%20and%20genomic%20data.%20%3Ci%3EProc%20Natl%20Acad%20Sci%20U%20S%20A%3C%5C%2Fi%3E%2C%20%3Ci%3E115%3C%5C%2Fi%3E%2824%29%2C%206249%26%23x2013%3B6254.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1073%5C%2Fpnas.1719358115%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1073%5C%2Fpnas.1719358115%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Comprehensive%20phylogeny%20of%20ray-finned%20fishes%20%28Actinopterygii%29%20based%20on%20transcriptomic%20and%20genomic%20data%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22L.%20C.%22%2C%22lastName%22%3A%22Hughes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Ort%5Cu00ed%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Y.%22%2C%22lastName%22%3A%22Huang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Y.%22%2C%22lastName%22%3A%22Sun%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%20C.%22%2C%22lastName%22%3A%22Baldwin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%20W.%22%2C%22lastName%22%3A%22Thompson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%20R.%22%2C%22lastName%22%3A%22Betancur%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%22%2C%22lastName%22%3A%22Li%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22L.%22%2C%22lastName%22%3A%22Becker%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22N.%22%2C%22lastName%22%3A%22Bellora%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22X.%22%2C%22lastName%22%3A%22Zhao%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22X.%22%2C%22lastName%22%3A%22Li%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Wang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%22%2C%22lastName%22%3A%22Fang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22B.%22%2C%22lastName%22%3A%22Xie%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Z.%22%2C%22lastName%22%3A%22Zhou%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22H.%22%2C%22lastName%22%3A%22Huang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S.%22%2C%22lastName%22%3A%22Chen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22B.%22%2C%22lastName%22%3A%22Venkatesh%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Q.%22%2C%22lastName%22%3A%22Shi%22%7D%5D%2C%22abstractNote%22%3A%22Our%20understanding%20of%20phylogenetic%20relationships%20among%20bony%20fishes%20has%20been%20transformed%20by%20analysis%20of%20a%20small%20number%20of%20genes%2C%20but%20uncertainty%20remains%20around%20critical%20nodes.%20Genome-scale%20inferences%20so%20far%20have%20sampled%20a%20limited%20number%20of%20taxa%20and%20genes.%20Here%20we%20leveraged%20144%20genomes%20and%20159%20transcriptomes%20to%20investigate%20fish%20evolution%20with%20an%20unparalleled%20scale%20of%20data%3A%20%3E0.5%20Mb%20from%201%2C105%20orthologous%20exon%20sequences%20from%20303%20species%2C%20representing%2066%20out%20of%2072%20ray-finned%20fish%20orders.%20We%20apply%20phylogenetic%20tests%20designed%20to%20trace%20the%20effect%20of%20whole-genome%20duplication%20events%20on%20gene%20trees%20and%20find%20paralogy-free%20loci%20using%20a%20bioinformatics%20approach.%20Genome-wide%20data%20support%20the%20structure%20of%20the%20fish%20phylogeny%2C%20and%20hypothesis-testing%20procedures%20appropriate%20for%20phylogenomic%20datasets%20using%20explicit%20gene%20genealogy%20interrogation%20settle%20some%20long-standing%20uncertainties%2C%20such%20as%20the%20branching%20order%20at%20the%20base%20of%20the%20teleosts%20and%20among%20early%20euteleosts%2C%20and%20the%20sister%20lineage%20to%20the%20acanthomorph%20and%20percomorph%20radiations.%20Comprehensive%20fossil%20calibrations%20date%20the%20origin%20of%20all%20major%20fish%20lineages%20before%20the%20end%20of%20the%20Cretaceous.%22%2C%22date%22%3A%22Jun%2012%202018%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1073%5C%2Fpnas.1719358115%22%2C%22ISSN%22%3A%220027-8424%20%28Print%29%200027-8424%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22BTBUS4GS%22%2C%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A32Z%22%7D%7D%2C%7B%22key%22%3A%22964TVPTK%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Arcila%20et%20al.%22%2C%22parsedDate%22%3A%222018%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3E%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20Petry%2C%20P.%2C%20%26amp%3B%20Ort%26%23xED%3B%2C%20G.%20%282018%29.%20Phylogenetic%20relationships%20of%20the%20family%20Tarumaniidae%20%28Characiformes%29%20based%20on%20nuclear%20and%20mitochondrial%20data.%20%3Ci%3ENeotropical%20Ichthyology%3C%5C%2Fi%3E%2C%20%3Ci%3E16%3C%5C%2Fi%3E%283%29.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2FArtn%20180016%2010.1590%5C%2F1982-0224-20180016%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2FArtn%20180016%2010.1590%5C%2F1982-0224-20180016%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Phylogenetic%20relationships%20of%20the%20family%20Tarumaniidae%20%28Characiformes%29%20based%20on%20nuclear%20and%20mitochondrial%20data%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22P.%22%2C%22lastName%22%3A%22Petry%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Ort%5Cu00ed%22%7D%5D%2C%22abstractNote%22%3A%22Characiformes%20is%20an%20order%20of%20freshwater%20fishes%20that%20includes%20many%20commercially%20important%20and%20emblematic%20species%20from%20South%20America%20and%20Africa%2C%20such%20as%20the%20popular%20piranhas%2C%20hatchetfishes%2C%20African%20tiger%20fishes%20and%20tetras.%20The%20order%20is%20split%20into%20two%20suborders%20with%20a%20total%20of%2024%20families%2C%20282%20genera%20and%20ca.%202%2C100%20species.%20Here%2C%20we%20present%20an%20expanded%20phylogeny%20of%20characiform%20fishes%2C%20including%20data%20for%20520%20species%20and%20three%20genes%20%2812S%2C%2016S%20and%20RAG1%29%2C%20and%20the%20recently%20described%20family%20Tarumaniidae%2C%20which%20has%20not%20been%20examined%20by%20previous%20molecular%20analysis.%20Although%20our%20genetic%20coverage%20is%20limited%20to%20three%20gene%20fragments%2C%20the%20tree%20inferred%20based%20on%20maximum%20likelihood%20and%20Bayesian%20inference%20supports%20the%20monophyly%20of%20all%20characiform%20families%20and%20is%20largely%20congruent%20with%20results%20from%20recent%20studies%20that%20sampled%20less%20taxa%20but%20more%20genes.%20Also%20in%20agreement%20with%20a%20morphological%20hypothesis%2C%20our%20results%20strongly%20support%20the%20sister-group%20relationships%20between%20the%20family%20Tarumaniidae%20and%20Erythrinidae.%20Based%20on%20our%20results%20and%20that%20of%20the%20other%20molecular%20analyses%2C%20we%20propose%20a%20revised%20circumscription%20of%20the%20superfamily%20Erythrinoidea%20to%20include%20the%20families%20Tarumaniidae%20and%20Erythrinidae%20only.%22%2C%22date%22%3A%222018%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%22Artn%20180016%2010.1590%5C%2F1982-0224-20180016%22%2C%22ISSN%22%3A%221679-6225%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A32Z%22%7D%7D%2C%7B%22key%22%3A%224LPXVC2G%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Arcila%20and%20Tyler%22%2C%22parsedDate%22%3A%222017-11-15%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3E%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20%26amp%3B%20Tyler%2C%20J.%20C.%20%282017%29.%20Mass%20extinction%20in%20tetraodontiform%20fishes%20linked%20to%20the%20Palaeocene-Eocene%20thermal%20maximum.%20%3Ci%3EProceedings%20of%20the%20Royal%20Society%20B-Biological%20Sciences%3C%5C%2Fi%3E%2C%20%3Ci%3E284%3C%5C%2Fi%3E%281866%29.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2FARTN%2020171771%2010.1098%5C%2Frspb.2017.1771%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2FARTN%2020171771%2010.1098%5C%2Frspb.2017.1771%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Mass%20extinction%20in%20tetraodontiform%20fishes%20linked%20to%20the%20Palaeocene-Eocene%20thermal%20maximum%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20C.%22%2C%22lastName%22%3A%22Tyler%22%7D%5D%2C%22abstractNote%22%3A%22Integrative%20evolutionary%20analyses%20based%20upon%20fossil%20and%20extant%20species%20provide%20a%20powerful%20approach%20for%20understanding%20past%20diversification%20events%20and%20for%20assessing%20the%20tempo%20of%20evolution%20across%20the%20Tree%20of%20Life.%20Herein%2C%20we%20demonstrate%20the%20importance%20of%20integrating%20fossil%20and%20extant%20species%20for%20inferring%20patterns%20of%20lineage%20diversification%20that%20would%20otherwise%20be%20masked%20in%20analyses%20that%20examine%20only%20one%20source%20of%20evidence.%20We%20infer%20the%20phylogeny%20and%20macroevolutionary%20history%20of%20the%20Tetraodontiformes%20%28triggerfishes%2C%20pufferfishes%20and%20allies%29%2C%20a%20group%20with%20one%20of%20the%20most%20extensive%20fossil%20records%20among%20fishes.%20Our%20analyses%20combine%20molecular%20and%20morphological%20data%2C%20based%20on%20an%20expanded%20matrix%20that%20adds%20newly%20coded%20fossil%20species%20and%20character%20states.%20Beyond%20confidently%20resolving%20the%20relationships%20and%20divergence%20times%20of%20tetraodontiforms%2C%20our%20diversification%20analyses%20detect%20a%20major%20mass-extinction%20event%20during%20the%20Palaeocene-Eocene%20Thermal%20Maximum%20%28PETM%29%2C%20followed%20by%20a%20marked%20increase%20in%20speciation%20rates.%20This%20pattern%20is%20consistently%20obtained%20when%20fossil%20and%20extant%20species%20are%20integrated%2C%20whereas%20examination%20of%20the%20fossil%20occurrences%20alone%20failed%20to%20detect%20major%20diversification%20changes%20during%20the%20PETM.%20When%20taking%20into%20account%20non-homogeneous%20models%2C%20our%20analyses%20also%20detect%20a%20rapid%20lineage%20diversification%20increase%20in%20one%20of%20the%20groups%20%28tetraodontoids%29%20during%20the%20middle%20Miocene%2C%20which%20is%20considered%20a%20key%20period%20in%20the%20evolution%20of%20reef%20fishes%20associated%20with%20trophic%20changes%20and%20ecological%20opportunity.%20In%20summary%2C%20our%20analyses%20show%20distinct%20diversification%20dynamics%20estimated%20from%20phylogenies%20and%20the%20fossil%20record%2C%20suggesting%20that%20different%20episodes%20shaped%20the%20evolution%20of%20tetraodontiforms%20during%20the%20Cenozoic.%22%2C%22date%22%3A%22Nov%2015%202017%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%22ARTN%2020171771%2010.1098%5C%2Frspb.2017.1771%22%2C%22ISSN%22%3A%220962-8452%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A33Z%22%7D%7D%2C%7B%22key%22%3A%22JG3BV32M%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Lavou%5Cu00e9%20et%20al.%22%2C%22parsedDate%22%3A%222017-08-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ELavou%26%23xE9%3B%2C%20S.%2C%20Arnegard%2C%20M.%20E.%2C%20Rabosky%2C%20D.%20L.%2C%20McIntyre%2C%20P.%20B.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20Vari%2C%20R.%20P.%2C%20%26amp%3B%20Nishida%2C%20M.%20%282017%29.%20Trophic%20evolution%20in%20African%20citharinoid%20fishes%20%28Teleostei%3A%20Characiformes%29%20and%20the%20origin%20of%20intraordinal%20pterygophagy.%20%3Ci%3EMolecular%20Phylogenetics%20and%20Evolution%3C%5C%2Fi%3E%2C%20%3Ci%3E113%3C%5C%2Fi%3E%2C%2023%26%23x2013%3B32.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2Fhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.ympev.2017.05.001%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2Fhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.ympev.2017.05.001%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Trophic%20evolution%20in%20African%20citharinoid%20fishes%20%28Teleostei%3A%20Characiformes%29%20and%20the%20origin%20of%20intraordinal%20pterygophagy%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S%5Cu00e9bastien%22%2C%22lastName%22%3A%22Lavou%5Cu00e9%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthew%20E.%22%2C%22lastName%22%3A%22Arnegard%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniel%20L.%22%2C%22lastName%22%3A%22Rabosky%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peter%20B.%22%2C%22lastName%22%3A%22McIntyre%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dahiana%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Richard%20P.%22%2C%22lastName%22%3A%22Vari%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mutsumi%22%2C%22lastName%22%3A%22Nishida%22%7D%5D%2C%22abstractNote%22%3A%22The%20African%20freshwater%20suborder%20Citharinoidei%20%28Characiformes%29%20includes%20110%20species%20that%20exhibit%20a%20diversity%20of%20feeding%20modes%20comparable%20to%20those%20characteristic%20of%20more%20speciose%20groups%20such%20its%20sister%2C%20the%20Characoidei%20%282000%2B%20species%29%20or%20the%20distantly%20related%20Cichlidae%20%281600%2B%20species%29.%20Feeding%20habits%20of%20the%20Citharinoidei%20range%20from%20generalist%20omnivores%20to%20highly%20specialized%20feeding%20modes%20including%20ectoparasitic%20fin-eating%2C%20i.e.%20pterygophagy.%20We%20examine%20diet%20preference%20evolution%20in%20the%20Citharinoidei%20using%20newly%20inferred%20multi-gene-based%20hypotheses%20of%20phylogenetic%20relationships%20for%20representatives%20of%2012%20of%20the%2015%20genera%20in%20the%20suborder.%20Ancestral%20character%20state%20reconstructions%20onto%20our%20best%20tree%20indicate%20that%20the%20three%20most-generalist%20diets%20-%20pelophage%5C%2Fplanktivore%2C%20omnivore%20and%20invertivore%20-%20are%20also%20the%20most%20primitive%20conditions%20within%20the%20Citharinoidei.%20The%20feeding%20mode%20of%20the%20most%20recent%20common%20ancestor%20of%20the%20Citharinoidei%20was%20characterized%20by%20high%20uncertainty.%20The%20more%20specialized%20feeding%20habits%20-%20herbivory%2C%20piscivory%20and%20pterygophagy%20-%20originated%20later%20in%20the%20Citharinoidei%2C%20likely%20from%20invertivore%20ancestors%20and%20possibly%20across%20a%20short%20time%20period.%20Highly%20specialized%20fin%20eaters%20%28Belonophago%2C%20Phago%20and%20Eugnatichthys%29%20share%20a%20common%20origin%20along%20with%20a%20strict%20piscivore%20%28Mesoborus%29%20and%20an%20invertivore%20%28Microstomatichthyoborus%29.%20The%20largely%20piscivorous%2C%20but%20facultative%20fin%20eater%2C%20Ichthyborus%20is%20not%20exclusively%20related%20to%20them.%20Our%20results%20demonstrate%20that%20overall%20diet%20preference%20transitions%20in%20the%20Citharinoidei%20were%20rare%20events%20with%20very%20few%20reversals%20or%20parallelisms%2C%20and%20that%20evolutionary%20shifts%20in%20trophic%20ecology%20have%20not%20played%20a%20major%20role%20in%20intraordinal%20diversification.%20This%20situation%20contrasts%20with%20other%20groups%20in%20which%20dietary%20transitions%20have%20played%20key%20roles%20in%20species%20diversification.%22%2C%22date%22%3A%222017%5C%2F08%5C%2F01%5C%2F%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.ympev.2017.05.001%22%2C%22ISSN%22%3A%221055-7903%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A33Z%22%7D%7D%2C%7B%22key%22%3A%22XPR2H5V5%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Arcila%20et%20al.%22%2C%22parsedDate%22%3A%222017-02%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3E%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20Orti%2C%20G.%2C%20Vari%2C%20R.%2C%20Armbruster%2C%20J.%20W.%2C%20Stiassny%2C%20M.%20L.%20J.%2C%20Ko%2C%20K.%20D.%2C%20Sabaj%2C%20M.%20H.%2C%20Lundberg%2C%20J.%2C%20Revell%2C%20L.%20J.%2C%20%26amp%3B%20Betancur%2C%20R.%20%282017%29.%20Genome-wide%20interrogation%20advances%20resolution%20of%20recalcitrant%20groups%20in%20the%20tree%20of%20life.%20%3Ci%3ENature%20Ecology%20%26amp%3B%20Evolution%3C%5C%2Fi%3E%2C%20%3Ci%3E1%3C%5C%2Fi%3E%282%29.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2FARTN%200020%2010.1038%5C%2Fs41559-016-0020%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2FARTN%200020%2010.1038%5C%2Fs41559-016-0020%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Genome-wide%20interrogation%20advances%20resolution%20of%20recalcitrant%20groups%20in%20the%20tree%20of%20life%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Orti%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Vari%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20W.%22%2C%22lastName%22%3A%22Armbruster%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%20L.%20J.%22%2C%22lastName%22%3A%22Stiassny%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22K.%20D.%22%2C%22lastName%22%3A%22Ko%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%20H.%22%2C%22lastName%22%3A%22Sabaj%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%22%2C%22lastName%22%3A%22Lundberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22L.%20J.%22%2C%22lastName%22%3A%22Revell%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Betancur%22%7D%5D%2C%22abstractNote%22%3A%22Much%20progress%20has%20been%20achieved%20in%20disentangling%20evolutionary%20relationships%20among%20species%20in%20the%20tree%20of%20life%2C%20but%20some%20taxonomic%20groups%20remain%20difficult%20to%20resolve%20despite%20increasing%20availability%20of%20genome-scale%20data%20sets.%20Here%20we%20present%20a%20practical%20approach%20to%20studying%20ancient%20divergences%20in%20the%20face%20of%20high%20levels%20of%20conflict%2C%20based%20on%20explicit%20gene%20genealogy%20interrogation%20%28GGI%29.%20We%20show%20its%20efficacy%20in%20resolving%20the%20controversial%20relationships%20within%20the%20largest%20freshwater%20fish%20radiation%20%28Otophysi%29%20based%20on%20newly%20generated%20DNA%20sequences%20for%201%2C051%20loci%20from%20225%20species.%20Initial%20results%20using%20a%20suite%20of%20standard%20methodologies%20revealed%20conflicting%20phylogenetic%20signal%2C%20which%20supports%20ten%20alternative%20evolutionary%20histories%20among%20early%20otophysan%20lineages.%20By%20contrast%2C%20GGI%20revealed%20that%20the%20vast%20majority%20of%20gene%20genealogies%20supports%20a%20single%20tree%20topology%20grounded%20on%20morphology%20that%20was%20not%20obtained%20by%20previous%20molecular%20studies.%20We%20also%20reanalysed%20published%20data%20sets%20for%20exemplary%20groups%20with%20recalcitrant%20resolution%20to%20assess%20the%20power%20of%20this%20approach.%20GGI%20supports%20the%20notion%20that%20ctenophores%20are%20the%20earliest-branching%20animal%20lineage%2C%20and%20adds%20insight%20into%20relationships%20within%20clades%20of%20yeasts%2C%20birds%20and%20mammals.%20GGI%20opens%20up%20a%20promising%20avenue%20to%20account%20for%20incompatible%20signals%20in%20large%20data%20sets%20and%20to%20discern%20between%20estimation%20error%20and%20actual%20biological%20conflict%20explaining%20gene%20tree%20discordance.%22%2C%22date%22%3A%22Feb%202017%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%22ARTN%200020%2010.1038%5C%2Fs41559-016-0020%22%2C%22ISSN%22%3A%222397-334x%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22BTBUS4GS%22%2C%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A33Z%22%7D%7D%2C%7B%22key%22%3A%223LNRLTID%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Bannikov%20et%20al.%22%2C%22parsedDate%22%3A%222017%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBannikov%2C%20A.%20F.%2C%20Tyler%2C%20J.%20C.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20%26amp%3B%20Carnevale%2C%20G.%20%282017%29.%20A%20new%20family%20of%20gymnodont%20fish%20%28Tetraodontiformes%29%20from%20the%20earliest%20Eocene%20of%20the%20Peri-Tethys%20%28Kabardino-Balkaria%2C%20northern%20Caucasus%2C%20Russia%29.%20%3Ci%3EJournal%20of%20Systematic%20Palaeontology%3C%5C%2Fi%3E%2C%20%3Ci%3E15%3C%5C%2Fi%3E%282%29%2C%20129%26%23x2013%3B146.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F14772019.2016.1149115%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F14772019.2016.1149115%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22A%20new%20family%20of%20gymnodont%20fish%20%28Tetraodontiformes%29%20from%20the%20earliest%20Eocene%20of%20the%20Peri-Tethys%20%28Kabardino-Balkaria%2C%20northern%20Caucasus%2C%20Russia%29%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%20F.%22%2C%22lastName%22%3A%22Bannikov%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20C.%22%2C%22lastName%22%3A%22Tyler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Carnevale%22%7D%5D%2C%22abstractNote%22%3A%22The%20environmental%20changes%20that%20occurred%20during%20the%20Paleocene-Eocene%20transition%20are%20crucial%20for%20the%20interpretation%20of%20the%20patterns%20and%20processes%20of%20diversification%20of%20vertebrate%20clades.%20A%20prominent%20increase%20of%20the%20number%20of%20vertebrate%20families%20occurred%20between%20the%20late%20Paleocene%20and%20early%20Eocene%2C%20resulting%20in%20the%20appearance%20of%20many%20in%20the%20earliest%20representatives%20of%20extant%20lineages%2C%20including%20a%20number%20of%20marine%20fish%20groups.%20Tetraodontiforms%20are%20a%20monophyletic%20group%20of%20derived%20teleost%20fishes%20encompassing%20a%20variety%20of%20bizarre%20morphologies.%20Even%20though%20the%20earliest%20members%20of%20this%20order%20appeared%20in%20the%20Late%20Cretaceous%2C%20most%20of%20the%20crown%20lineages%20date%20back%20to%20the%20Eocene.%20One%20of%20the%20crown%20tetraodontiform%20groups%20that%20appeared%20in%20the%20fossil%20record%20during%20the%20Eocene%20are%20the%20gymnodonts%20%28pufferfishes%2C%20porcupinefishes%2C%20ocean%20sunfishes%20and%20their%20allies%29%2C%20which%20include%20a%20variety%20of%20species%20characterized%20by%20highly%20modified%20teeth%20incorporated%20into%20beak-like%20jaws%20and%20scales%20usually%20modified%20into%20prickly%20spines.%20Herein%2C%20we%20describe%20dagger%20Balkaria%20histiopterygia%20gen.%20et%20sp.%20nov.%2C%20a%20gymnodont%20fish%20characterized%20by%20a%20strikingly%20peculiar%20morphology.%20The%20single%20available%20specimen%20in%20part%20and%20counterpart%20documented%20herein%20was%20recovered%20from%20the%20sapropelitic%20deposits%20that%20originated%20in%20the%20northern%20Peri-Tethys%20during%20the%20transition%20between%20the%20Paleocene%20and%20Eocene.%20Today%2C%20these%20deposits%20are%20exposed%20near%20the%20village%20of%20Gerpegezh%2C%20Republic%20of%20Kabardino-Balkaria%2C%20Russia.%20The%20skeletal%20structure%20reveals%20an%20extreme%20mosaicism%20of%20primitive%20and%20derived%20characters%20that%20result%20in%20a%20very%20bizarre%20and%20unexpected%20morphology.%20dagger%20Balkaria%20histiopterygia%20gen.%20et%20sp.%20nov.%20is%20unique%20among%20the%20extant%20and%20other%20fossil%20gymnodont%20fishes%20by%2C%20among%20many%20other%20features%2C%20the%20huge%20size%20of%20itsspiny-dorsal%20fin%20and%20the%20position%20of%20these%20spines%20on%20the%20top%20of%20the%20head.%20dagger%20Balkaria%20histiopterygia%20gen.%20et%20sp.%20nov.%20is%20the%20earliest%20unequivocal%20gymnodont%20fish%2C%20representing%20the%20sole%20member%20of%20the%20new%20family%20dagger%20Balkariidae.%20More%20particularly%2C%20dagger%20Balkaria%20histiopterygia%20gen.%20et%20sp.%20nov.%20is%20shown%20herein%20to%20be%20the%20oldest%20and%20arguably%20the%20most%20informative%20fossil%20of%20the%20gymnodont%20suborder%20Tetraodontoidei.%20The%20phylogenetic%20placement%20of%20this%20new%20taxon%20has%20been%20assessed%20based%20on%20both%20morphology%20alone%20and%20on%20a%20combination%20of%20morphological%20and%20molecular%20data%20that%20strongly%20supports%20the%20close%20relationship%20of%20dagger%20Balkaria%20gen.%20nov.%20to%20the%20herein%20restricted%20Tetraodontoidei.%20However%2C%20its%20position%20within%20Tetraodontoidei%20is%20unstable%20depending%20on%20the%20type%20of%20method%20of%20phylogenetic%20inference.%20Significantly%20younger%20ages%2C%20during%20the%20Late%20Cretaceous%2C%20are%20estimated%20for%20the%20diversification%20of%20Tetraodontiformes%20than%20in%20previous%20tip-dating%20analyses%20%28Jurassic%20and%20Early%20Cretaceous%29%20using%20the%20fossilized%20birth-death%20process%3B%20these%20new%20age%20estimates%20are%20in%20better%20agreement%20with%20the%20tetraodontiform%20fossil%20record.http%3A%5C%2F%5C%2Fzoobank.org%5C%2Furn%3Alsid%3Azoobank.org%3Apub%3A41764800-B0D8-4CA4-A111-5F4C4A281C37%22%2C%22date%22%3A%222017%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%2210.1080%5C%2F14772019.2016.1149115%22%2C%22ISSN%22%3A%221477-2019%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A33Z%22%7D%7D%2C%7B%22key%22%3A%223W35W5Y9%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Thomaz%20et%20al.%22%2C%22parsedDate%22%3A%222015-07-21%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EThomaz%2C%20A.%20T.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20Ort%26%23xED%3B%2C%20G.%2C%20%26amp%3B%20Malabarba%2C%20L.%20R.%20%282015%29.%20Molecular%20phylogeny%20of%20the%20subfamily%20Stevardiinae%20Gill%2C%201858%20%28Characiformes%3A%20Characidae%29%3A%20classification%20and%20the%20evolution%20of%20reproductive%20traits.%20%3Ci%3EBmc%20Evolutionary%20Biology%3C%5C%2Fi%3E%2C%20%3Ci%3E15%3C%5C%2Fi%3E.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2FARTN%20146%2010.1186%5C%2Fs12862-015-0403-4%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2FARTN%20146%2010.1186%5C%2Fs12862-015-0403-4%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Molecular%20phylogeny%20of%20the%20subfamily%20Stevardiinae%20Gill%2C%201858%20%28Characiformes%3A%20Characidae%29%3A%20classification%20and%20the%20evolution%20of%20reproductive%20traits%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%20T.%22%2C%22lastName%22%3A%22Thomaz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Ort%5Cu00ed%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22L.%20R.%22%2C%22lastName%22%3A%22Malabarba%22%7D%5D%2C%22abstractNote%22%3A%22Background%3A%20The%20subfamily%20Stevardiinae%20is%20a%20diverse%20and%20widely%20distributed%20clade%20of%20freshwater%20fishes%20from%20South%20and%20Central%20America%2C%20commonly%20known%20as%20%5C%22tetras%5C%22%20%28Characidae%29.%20The%20group%20was%20named%20%5C%22clade%20A%5C%22%20when%20first%20proposed%20as%20a%20monophyletic%20unit%20of%20Characidae%20and%20later%20designated%20as%20a%20subfamily.%20Stevardiinae%20includes%2048%20genera%20and%20around%20310%20valid%20species%20with%20many%20species%20presenting%20inseminating%20reproductive%20strategy.%20No%20global%20hypothesis%20of%20relationships%20is%20available%20for%20this%20group%20and%20currently%20many%20genera%20are%20listed%20as%20incertae%20sedis%20or%20are%20suspected%20to%20be%20non-monophyletic.%5CnResults%3A%20We%20present%20a%20molecular%20phylogeny%20with%20the%20largest%20number%20of%20stevardiine%20species%20analyzed%20so%20far%2C%20including%20355%20samples%20representing%20153%20putative%20species%20distributed%20in%2032%20genera%2C%20to%20test%20the%20group%27s%20monophyly%20and%20internal%20relationships.%20The%20phylogeny%20was%20inferred%20using%20DNA%20sequence%20data%20from%20seven%20gene%20fragments%20%28mtDNA%3A%2012S%2C%2016S%20and%20COI%3B%20nuclear%3A%20RAG1%2C%20RAG2%2C%20MYH6%20and%20PTR%29.%20The%20results%20support%20the%20Stevardiinae%20as%20a%20monophyletic%20group%20and%20a%20detailed%20hypothesis%20of%20the%20internal%20relationships%20for%20this%20subfamily.%5CnConclusions%3A%20A%20revised%20classification%20based%20on%20the%20molecular%20phylogeny%20is%20proposed%20that%20includes%20seven%20tribes%20and%20also%20defines%20monophyletic%20genera%2C%20including%20a%20resurrected%20genus%20Eretmobrycon%2C%20and%20new%20definitions%20for%20Diapoma%2C%20Hemibrycon%2C%20Bryconamericus%20sensu%20stricto%2C%20and%20Knodus%20sensu%20stricto%2C%20placing%20some%20small%20genera%20as%20junior%20synonyms.%20Inseminating%20species%20are%20distributed%20in%20several%20clades%20suggesting%20that%20reproductive%20strategy%20is%20evolutionarily%20labile%20in%20this%20group%20of%20fishes.%22%2C%22date%22%3A%22Jul%2021%202015%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%22ARTN%20146%2010.1186%5C%2Fs12862-015-0403-4%22%2C%22ISSN%22%3A%221471-2148%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A33Z%22%7D%7D%2C%7B%22key%22%3A%22FINL5AZL%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Arcila%20et%20al.%22%2C%22parsedDate%22%3A%222015-01%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3E%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20Pyron%2C%20R.%20A.%2C%20Tyler%2C%20J.%20C.%2C%20Ort%26%23xED%3B%2C%20G.%2C%20%26amp%3B%20Betancur-R%2C%20R.%20%282015%29.%20An%20evaluation%20of%20fossil%20tip-dating%20versus%20node-age%20calibrations%20in%20tetraodontiform%20fishes%20%28Teleostei%3A%20Percomorphaceae%29.%20%3Ci%3EMolecular%20Phylogenetics%20and%20Evolution%3C%5C%2Fi%3E%2C%20%3Ci%3E82%3C%5C%2Fi%3E%2C%20131%26%23x2013%3B145.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.ympev.2014.10.011%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.ympev.2014.10.011%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22An%20evaluation%20of%20fossil%20tip-dating%20versus%20node-age%20calibrations%20in%20tetraodontiform%20fishes%20%28Teleostei%3A%20Percomorphaceae%29%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%20A.%22%2C%22lastName%22%3A%22Pyron%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20C.%22%2C%22lastName%22%3A%22Tyler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Ort%5Cu00ed%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Betancur-R%22%7D%5D%2C%22abstractNote%22%3A%22Time-calibrated%20phylogenies%20based%20on%20molecular%20data%20provide%20a%20framework%20for%20comparative%20studies.%20Calibration%20methods%20to%20combine%20fossil%20information%20with%20molecular%20phylogenies%20are%2C%20however%2C%20under%20active%20development%2C%20often%20generating%20disagreement%20about%20the%20best%20way%20to%20incorporate%20paleontological%20data%20into%20these%20analyses.%20This%20study%20provides%20an%20empirical%20comparison%20of%20the%20most%20widely%20used%20approach%20based%20on%20node-dating%20priors%20for%20relaxed%20clocks%20implemented%20in%20the%20programs%20BEAST%20and%20MrBayes%2C%20with%20two%20recently%20proposed%20improvements%3A%20one%20using%20a%20new%20fossilized%20birth-death%20process%20model%20for%20node%20dating%20%28implemented%20in%20the%20program%20DPPDiv%29%2C%20and%20the%20other%20using%20a%20total-evidence%20or%20tip-dating%20method%20%28implemented%20in%20MrBayes%20and%20BEAST%29.%20These%20methods%20are%20applied%20herein%20to%20tetraodontiform%20fishes%2C%20a%20diverse%20group%20of%20living%20and%20extinct%20taxa%20that%20features%20one%20of%20the%20most%20extensive%20fossil%20records%20among%20teleosts.%20Previous%20estimates%20of%20time-calibrated%20phylogenies%20of%20tetraodontiforms%20using%20node-dating%20methods%20reported%20disparate%20estimates%20for%20their%20age%20of%20origin%2C%20ranging%20from%20the%20late%20Jurassic%20to%20the%20early%20Paleocene%20%28ca.%20150-59%20Ma%29.%20We%20analyzed%20a%20comprehensive%20dataset%20with%2016%20loci%20and%20210%20morphological%20characters%2C%20including%20131%20taxa%20%2895%20extant%20and%2036%20fossil%20species%29%20representing%20all%20families%20of%20fossil%20and%20extant%20tetraodontiforms%2C%20under%20different%20molecular%20clock%20calibration%20approaches.%20Results%20from%20node-dating%20methods%20produced%20consistently%20younger%20ages%20than%20the%20tip-dating%20approaches.%20The%20older%20ages%20inferred%20by%20tip%20dating%20imply%20an%20unlikely%20early-late%20Jurassic%20%28ca.%20185-119%20Ma%29%20origin%20for%20this%20order%20and%20the%20existence%20of%20extended%20ghost%20lineages%20in%20their%20fossil%20record.%20Node-based%20methods%2C%20by%20contrast%2C%20produce%20time%20estimates%20that%20are%20more%20consistent%20with%20the%20stratigraphic%20record%2C%20suggesting%20a%20late%20Cretaceous%20%28ca.%2086-96%20Ma%29%20origin.%20We%20show%20that%20the%20precision%20of%20clade%20age%20estimates%20using%20tip%20dating%20increases%20with%20the%20number%20of%20fossils%20analyzed%20and%20with%20the%20proximity%20of%20fossil%20taxa%20to%20the%20node%20under%20assessment.%20This%20study%20suggests%20that%20current%20implementations%20of%20tip%20dating%20may%20overestimate%20ages%20of%20divergence%20in%20calibrated%20phylogenies.%20It%20also%20provides%20a%20comprehensive%20phylogenetic%20framework%20for%20tetraodontiform%20systematics%20and%20future%20comparative%20studies.%20%28C%29%202014%20Elsevier%20Inc.%20All%20rights%20reserved.%22%2C%22date%22%3A%22Jan%202015%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.ympev.2014.10.011%22%2C%22ISSN%22%3A%221055-7903%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22BTBUS4GS%22%2C%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A33Z%22%7D%7D%2C%7B%22key%22%3A%22GR3V2H95%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Arcila%20et%20al.%22%2C%22parsedDate%22%3A%222013-12-30%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3E%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20Vari%2C%20R.%20P.%2C%20%26amp%3B%20Menezes%2C%20N.%20A.%20%282013%29.%20Revision%20of%20the%20Neotropical%20Genus%20%28Ostariophysi%3A%20Characiformes%3A%20Characidae%29%20with%20Description%20of%20Two%20New%20Species.%20%3Ci%3ECopeia%3C%5C%2Fi%3E%2C%20%3Ci%3E4%3C%5C%2Fi%3E%2C%20604%26%23x2013%3B611.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1643%5C%2FCi-13-009%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1643%5C%2FCi-13-009%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Revision%20of%20the%20Neotropical%20Genus%20%28Ostariophysi%3A%20Characiformes%3A%20Characidae%29%20with%20Description%20of%20Two%20New%20Species%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%20P.%22%2C%22lastName%22%3A%22Vari%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22N.%20A.%22%2C%22lastName%22%3A%22Menezes%22%7D%5D%2C%22abstractNote%22%3A%22Acrobrycon%2C%20a%20genus%20of%20Neotropical%20freshwater%20fishes%20from%20the%20western%20Amazon%20and%20northwestern%20portions%20of%20the%20La%20Plata%20basin%20is%20revised.%20The%20genus%20is%20found%20to%20include%20three%20species%2C%20two%20of%20which%20are%20new%20to%20science.%20Acrobrycon%20ipanquianus%20is%20distributed%20from%20the%20western%20portions%20of%20the%20Rio%20Amazonas%20through%20to%20the%20northwestern%20region%20of%20the%20Rio%20de%20La%20Plata%20basin%3B%20A.%20starnesi%2C%20new%20species%2C%20in%20the%20southwestern%20portion%20of%20the%20Amazon%20basin%20in%20Bolivia%3B%20and%20A.%20ortii%2C%20new%20species%2C%20in%20the%20northwestern%20Rio%20de%20La%20Plata%20basin%20in%20Argentina.%20Members%20of%20the%20genus%20are%20distinguished%20from%20each%20other%20on%20the%20basis%20of%20the%20depth%20at%20the%20dorsal-fin%20origin%2C%20the%20horizontal%20eye%20diameter%2C%20the%20least%20interorbital%20width%2C%20and%20the%20numbers%20of%20perforated%20lateral-line%20scales%2C%20anal-fin%20rays%2C%20and%20horizontal%20scales%20around%20the%20caudal%20peduncle.%20The%20analysis%20found%20that%20A.%20tarijae%2C%20described%20from%20the%20Rio%20Lipeo%20in%20Bolivia%2C%20cannot%20be%20distinguished%20morphologically%20from%20A.%20ipanquianus%3B%20thus%2C%20A.%20tarijae%20is%20placed%20into%20the%20synonymy%20of%20A.%20ipanquianus.%22%2C%22date%22%3A%22Dec%2030%202013%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%2210.1643%5C%2FCi-13-009%22%2C%22ISSN%22%3A%220045-8511%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A33Z%22%7D%7D%2C%7B%22key%22%3A%22A94ZYCD6%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Betancur-R%20et%20al.%22%2C%22parsedDate%22%3A%222013%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBetancur-R%2C%20R.%2C%20Broughton%2C%20R.%20E.%2C%20Wiley%2C%20E.%20O.%2C%20Carpenter%2C%20K.%2C%20L%26%23xF3%3Bpez%2C%20J.%20A.%2C%20Li%2C%20C.%20H.%2C%20Holcroft%2C%20N.%20I.%2C%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%2C%20Sanciangco%2C%20M.%2C%20Cureton%2C%20J.%20C.%2C%20Zhang%2C%20F.%20F.%2C%20Buser%2C%20T.%2C%20Campbell%2C%20M.%20A.%2C%20Ballesteros%2C%20J.%20A.%2C%20Roa-Varon%2C%20A.%2C%20Willis%2C%20S.%2C%20Borden%2C%20W.%20C.%2C%20Rowley%2C%20T.%2C%20Reneau%2C%20P.%20C.%2C%20%26%23x2026%3B%20Ort%26%23xED%3B%2C%20G.%20%282013%29.%20The%20Tree%20of%20Life%20and%20a%20New%20Classification%20of%20Bony%20Fishes.%20%3Ci%3EPlos%20Currents-Tree%20of%20Life%3C%5C%2Fi%3E.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fcurrents.tol.53ba26640df0ccaee75bb165c8c26288%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fcurrents.tol.53ba26640df0ccaee75bb165c8c26288%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20Tree%20of%20Life%20and%20a%20New%20Classification%20of%20Bony%20Fishes%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Betancur-R%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%20E.%22%2C%22lastName%22%3A%22Broughton%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22E.%20O.%22%2C%22lastName%22%3A%22Wiley%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22K.%22%2C%22lastName%22%3A%22Carpenter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20A.%22%2C%22lastName%22%3A%22L%5Cu00f3pez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%20H.%22%2C%22lastName%22%3A%22Li%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22N.%20I.%22%2C%22lastName%22%3A%22Holcroft%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Arcila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Sanciangco%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20C.%22%2C%22lastName%22%3A%22Cureton%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22F.%20F.%22%2C%22lastName%22%3A%22Zhang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22T.%22%2C%22lastName%22%3A%22Buser%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%20A.%22%2C%22lastName%22%3A%22Campbell%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20A.%22%2C%22lastName%22%3A%22Ballesteros%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Roa-Varon%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S.%22%2C%22lastName%22%3A%22Willis%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%20C.%22%2C%22lastName%22%3A%22Borden%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22T.%22%2C%22lastName%22%3A%22Rowley%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22P.%20C.%22%2C%22lastName%22%3A%22Reneau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%20J.%22%2C%22lastName%22%3A%22Hough%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%20Q.%22%2C%22lastName%22%3A%22Lu%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22T.%22%2C%22lastName%22%3A%22Grande%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Arratia%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Ort%5Cu00ed%22%7D%5D%2C%22abstractNote%22%3A%22The%20tree%20of%20life%20of%20fishes%20is%20in%20a%20state%20of%20flux%20because%20we%20still%20lack%20a%20comprehensive%20phylogeny%20that%20includes%20all%20major%20groups.%20The%20situation%20is%20most%20critical%20for%20a%20large%20clade%20of%20spiny-finned%20fishes%2C%20traditionally%20referred%20to%20as%20percomorphs%2C%20whose%20uncertain%20relationships%20have%20plagued%20ichthyologists%20for%20over%20a%20century.%20Most%20of%20what%20we%20know%20about%20the%20higher-level%20relationships%20among%20fish%20lineages%20has%20been%20based%20on%20morphology%2C%20but%20rapid%20influx%20of%20molecular%20studies%20is%20changing%20many%20established%20systematic%20concepts.%20We%20report%20a%20comprehensive%20molecular%20phylogeny%20for%20bony%20fishes%20that%20includes%20representatives%20of%20all%20major%20lineages.%20DNA%20sequence%20data%20for%2021%20molecular%20markers%20%28one%20mitochondrial%20and%2020%20nuclear%20genes%29%20were%20collected%20for%201410%20bony%20fish%20taxa%2C%20plus%20four%20tetrapod%20species%20and%20two%20chondrichthyan%20outgroups%20%28total%201416%20terminals%29.%20Bony%20fish%20diversity%20is%20represented%20by%201093%20genera%2C%20369%20families%2C%20and%20all%20traditionally%20recognized%20orders.%20The%20maximum%20likelihood%20tree%20provides%20unprecedented%20resolution%20and%20high%20bootstrap%20support%20for%20most%20backbone%20nodes%2C%20defining%20for%20the%20first%20time%20a%20global%20phylogeny%20of%20fishes.%20The%20general%20structure%20of%20the%20tree%20is%20in%20agreement%20with%20expectations%20from%20previous%20morphological%20and%20molecular%20studies%2C%20but%20significant%20new%20clades%20arise.%20Most%20interestingly%2C%20the%20high%20degree%20of%20uncertainty%20among%20percomorphs%20is%20now%20resolved%20into%20nine%20well-supported%20supraordinal%20groups.%20The%20order%20Perciformes%2C%20considered%20by%20many%20a%20polyphyletic%20taxonomic%20waste%20basket%2C%20is%20defined%20for%20the%20first%20time%20as%20a%20monophyletic%20group%20in%20the%20global%20phylogeny.%20A%20new%20classification%20that%20reflects%20our%20phylogenetic%20hypothesis%20is%20proposed%20to%20facilitate%20communication%20about%20the%20newly%20found%20structure%20of%20the%20tree%20of%20life%20of%20fishes.%20Finally%2C%20the%20molecular%20phylogeny%20is%20calibrated%20using%2060%20fossil%20constraints%20to%20produce%20a%20comprehensive%20time%20tree.%20The%20new%20time-calibrated%20phylogeny%20will%20provide%20the%20basis%20for%20and%20stimulate%20new%20comparative%20studies%20to%20better%20understand%20the%20evolution%20of%20the%20amazing%20diversity%20of%20fishes.%22%2C%22date%22%3A%222013%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%2210.1371%5C%2Fcurrents.tol.53ba26640df0ccaee75bb165c8c26288%22%2C%22ISSN%22%3A%222157-3999%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22BTBUS4GS%22%2C%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A33Z%22%7D%7D%2C%7B%22key%22%3A%22UFHRG6BU%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Rom%5Cu221a%5Cu00b0n-Valencia%20and%20Arcila-Mesa%22%2C%22parsedDate%22%3A%222010%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ERom%26%23x221A%3B%26%23xB0%3Bn-Valencia%2C%20C.%2C%20%26amp%3B%20Arcila-Mesa%2C%20D.%20K.%20%282010%29.%20Five%20new%20species%20of%20Hemibrycon%20%28Characiformes%3A%20Characidae%29%20from%20the%20Rio%20Magdalena%20basin%2C%20Colombia.%20%3Ci%3ERevista%20de%20Biolog%26%23xCC%3Ba%20Tropical%3C%5C%2Fi%3E%2C%20%3Ci%3E58%3C%5C%2Fi%3E%2C%20339%2B.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Five%20new%20species%20of%20Hemibrycon%20%28Characiformes%3A%20Characidae%29%20from%20the%20Rio%20Magdalena%20basin%2C%20Colombia%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C%5Cu221a%5Cu00a9sar%22%2C%22lastName%22%3A%22Rom%5Cu221a%5Cu00b0n-Valencia%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dahiana%20K.%22%2C%22lastName%22%3A%22Arcila-Mesa%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222010%5C%2F03%5C%2F%5C%2F%20%5C%2F%5C%2F%22%2C%22language%22%3A%22Spanish%22%2C%22DOI%22%3A%22%22%2C%22ISSN%22%3A%2200347744%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A33Z%22%7D%7D%2C%7B%22key%22%3A%22U4UTYZG5%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Rom%5Cu00e1n-%20Valencia%20and%20Arcila%22%2C%22parsedDate%22%3A%222009%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ERom%26%23xE1%3Bn-%20Valencia%2C%20C.%2C%20%26amp%3B%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%20%282009%29.%20Two%20new%20species%20of%20Hemibrycon%20%28Characiformes%2C%20Characidae%29%20from%20the%20Magdalena%20River%2C%20Colombia.%20%3Ci%3EAnimal%20Biodiversity%20and%20Conservation%3C%5C%2Fi%3E%2C%20%3Ci%3E32%3C%5C%2Fi%3E.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.32800%5C%2Fabc.2009.32.0077%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.32800%5C%2Fabc.2009.32.0077%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Two%20new%20species%20of%20Hemibrycon%20%28Characiformes%2C%20Characidae%29%20from%20the%20Magdalena%20River%2C%20Colombia%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Cesar%22%2C%22lastName%22%3A%22Rom%5Cu00e1n-%20Valencia%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dahiana%22%2C%22lastName%22%3A%22Arcila%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%2212%5C%2F01%202009%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.32800%5C%2Fabc.2009.32.0077%22%2C%22ISSN%22%3A%22%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A33Z%22%7D%7D%2C%7B%22key%22%3A%22PELMWXYU%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Rom%5Cu00e1n-Valencia%20et%20al.%22%2C%22parsedDate%22%3A%222009%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ERom%26%23xE1%3Bn-Valencia%2C%20C.%2C%20Arcila-Mesa%2C%20D.%20K.%2C%20%26amp%3B%20Hurtado%20T%2C%20H.%20%282009%29.%20Variaci%26%23xF3%3Bn%20morfol%26%23xF3%3Bgica%20de%20los%20peces%20Hemibrycon%20boquiae%20y%20Hemibrycon%20rafaelense%20%28Characiformes%3A%20Characidae%29%20en%20el%20R%26%23xED%3Bo%20Cauca%2C%20Colombia.%20%3Ci%3ERevista%20de%20Biolog%26%23xCC%3Ba%20Tropical%3C%5C%2Fi%3E%2C%20%3Ci%3E57%3C%5C%2Fi%3E%283%29%2C%20541%26%23x2013%3B556.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Variaci%5Cu00f3n%20morfol%5Cu00f3gica%20de%20los%20peces%20Hemibrycon%20boquiae%20y%20Hemibrycon%20rafaelense%20%28Characiformes%3A%20Characidae%29%20en%20el%20R%5Cu00edo%20Cauca%2C%20Colombia%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C%5Cu00e9sar%22%2C%22lastName%22%3A%22Rom%5Cu00e1n-Valencia%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dahiana%20K.%22%2C%22lastName%22%3A%22Arcila-Mesa%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hernando%22%2C%22lastName%22%3A%22Hurtado%20T%22%7D%5D%2C%22abstractNote%22%3A%22Analizamos%20la%20variaci%5Cu00f3n%20morfol%5Cu00f3gica%20y%20osteol%5Cu00f3gica%20en%20Hemibrycon%20boquiae%20y%20H.%20rafaelense%20en%20la%20cuenca%20del%20r%5Cu00edo%20Cauca.%20Los%20an%5Cu00e1lisis%20multivariados%20determinan%20poblaciones%20de%20H.%20boquiae%20en%20las%20quebradas%3A%20Boquiae%2C%20Honda%2C%20Las%20%5Cu00c1guilas%2C%20Do%5Cu00f1a%20Juana%2C%20Villa%20Paola%2C%20Portachuelo%2C%20La%20V%5Cu00edbora%2C%20Aimes%20y%20Ram%5Cu00edrez%20y%20poblaciones%20de%20H.%20rafaelense%20en%20las%20quebradas%3A%20Canceles%2C%20La%20Clara%2C%20San%20Rafael%20y%20San%20Jos%5Cu00e9.%20No%20hay%20diferencias%20en%20la%20morfometr%5Cu00eda%20entre%20las%20poblaciones%20de%20H.%20boquiae%20y%20H.%20rafaelense.%20Se%20presentan%20discrepancias%20mer%5Cu00edsticas%20significativas%20para%20las%20poblaciones%20de%20H.%20boquiae%20%28n%3D%20277%29%20y%20H.%20rafaelense%20%28n%3D%20121%29%20en%3A%20n%5Cu00famero%20de%20escamas%20entre%20la%20l%5Cu00ednea%20lateral%20y%20la%20aleta%20anal%2C%20y%20n%5Cu00famero%20de%20escamas%20entre%20la%20l%5Cu00ednea%20lateral%20y%20la%20aleta%20p%5Cu00e9lvica.%20La%20distancia%20de%20similaridad%20del%20an%5Cu00e1lisis%20de%20agrupamiento%20%28%5C%22cluster%5C%22%29%20para%20los%20caracteres%20osteol%5Cu00f3gicos%2C%20al%20igual%20que%20el%20n%5Cu00famero%20de%20escamas%20predorsales%2C%20apoyan%20la%20existencia%20de%20dos%20grupos%20discretos%20que%20corresponden%20a%20H.%20boquiae%20y%20H.%20rafaelense.%20We%20analyzed%20the%20variation%20in%20morphological%20and%20osteological%20characteristics%20of%20Hemibrycon%20boquiae%20and%20Hemibrycon%20rafaelense%20in%20the%20Cauca%20River.%20The%20multivariate%20analysis%20determined%20populations%20of%20H.%20boquiae%20in%20nine%20streams%3A%20Boquier%2C%20Honda%2C%20Las%20Aguilas%2C%20Do%5Cu00f1a%20Juana%2C%20Villa%20Paola%2C%20Portachuelo%2C%20The%20Snake%2C%20Aimes%20and%20Ramirez%2C%20and%20populations%20of%20H.%20rafaelense%20in%20four%20streams%3A%20Canceles%2C%20Clara%2C%20San%20Rafael%20and%20San%20Jose.%20There%20were%20morphometric%20differences%20among%20populations%20of%20H.%20boquiae%20%28n%3D%20277%29%20and%20H.%20rafaelense%20%28n%3D%20121%29.%20Nevertheless%2C%20there%20were%20significant%20meristic%20discrepancies%20among%20populations%20of%20both%20species%3A%20number%20of%20scales%20between%20lateral%20line%20and%20anal%20fin%2C%20and%20number%20of%20scales%20between%20lateral%20line%20and%20pelvic%20fin.%20The%20absence%20of%20bilateral%20symmetry%20was%20observed%20in%20the%20number%20of%20maxillary%20teeth%20in%20H.%20boquiae.%20The%20cluster%20analysis%20distance%20for%20osteological%20characters%2C%20including%20the%20number%20of%20predorsal%20scales%2C%20separated%20H.%20boquiae%20and%20H.%20rafaelense%20in%20two%20defined%20groups.%22%2C%22date%22%3A%222009%22%2C%22language%22%3A%22Espa%5Cu00f1ol%22%2C%22DOI%22%3A%22%22%2C%22ISSN%22%3A%220034-7744%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A33Z%22%7D%7D%2C%7B%22key%22%3A%22Q3CYXBPX%22%2C%22library%22%3A%7B%22id%22%3A9129767%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Rom%5Cu00e1n-%20Valencia%20and%20Arcila%22%2C%22parsedDate%22%3A%222008%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ERom%26%23xE1%3Bn-%20Valencia%2C%20C.%2C%20%26amp%3B%20%3Cstrong%3EArcila%2C%20D.%3C%5C%2Fstrong%3E%20%282008%29.%20Hemibrycon%20rafaelense%20n.%20sp.%20%28Characiformes%2C%20Characidae%29%2C%20a%20new%20species%20from%20the%20upper%20Cauca%20River%2C%20with%20keys%20to%20Colombian%20species.%20%3Ci%3EAnimal%20Biodiversity%20and%20Conservation%3C%5C%2Fi%3E%2C%20%3Ci%3E31%3C%5C%2Fi%3E.%20%3Ca%20class%3D%27zp-DOIURL%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.32800%5C%2Fabc.2008.31.0067%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.32800%5C%2Fabc.2008.31.0067%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Hemibrycon%20rafaelense%20n.%20sp.%20%28Characiformes%2C%20Characidae%29%2C%20a%20new%20species%20from%20the%20upper%20Cauca%20River%2C%20with%20keys%20to%20Colombian%20species%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Cesar%22%2C%22lastName%22%3A%22Rom%5Cu00e1n-%20Valencia%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dahiana%22%2C%22lastName%22%3A%22Arcila%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%2206%5C%2F01%202008%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.32800%5C%2Fabc.2008.31.0067%22%2C%22ISSN%22%3A%22%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2276CNVERS%22%5D%2C%22dateModified%22%3A%222024-01-08T23%3A40%3A33Z%22%7D%7D%5D%7D
Santaquiteria, A., Miller, E. C., Rosas-Puchuri, U., Pedraza-Marrón, C. D. R., Troyer, E. M., Westneat, M. W., Carnevale, G., Arcila, D., & Betancur-R., R. (2025). Colonization Dynamics Explain the Decoupling of Species Richness and Morphological Disparity in Syngnatharian Fishes across Oceans. The American Naturalist, E000–E000. https://doi.org/10.1086/733931
Miller, E. C., Faucher, R., Hart, P. B., Rincón-Sandoval, M., Santaquiteria, A., White, W. T., Baldwin, C. C., Miya, M., Betancur-R, R., Tornabene, L., Evans, K., & Arcila, D. (2024). Reduced evolutionary constraint accompanies ongoing radiation in deep-sea anglerfishes. Nature Ecology & Evolution. https://doi.org/10.1038/s41559-024-02586-3
Rincon-Sandoval, M., De-Kayne, R., Shank, S. D., Pirro, S., Ko’ou, A., Abueg, L., Tracey, A., Mountcastle, J., O’Toole, B., Balacco, J., Formenti, G., Jarvis, E. D., Arcila, D., Kosakovsky Pond, S. L., Davis, A., Bloom, D. D., & Betancur-R, R. (2024). Ecological diversification of sea catfishes is accompanied by genome-wide signatures of positive selection. Nature Communications, 15(1), 10040. https://doi.org/10.1038/s41467-024-54184-3
Troyer, E. M., Evans, K. M., Goatley, C. H. R., Friedman, M., Carnevale, G., Nicholas, B., Kolmann, M., Bemis, K. E., & Arcila, D. (2024). Evolutionary innovation accelerates morphological diversification in pufferfishes and their relatives. Evolution, qpae127. https://doi.org/10.1093/evolut/qpae127
Duarte-Ribeiro, E., Rosas-Puchuri, U., Friedman, M., Woodruff, G. C., Hughes, L. C., Carpenter, K. E., White, W. T., Pogonoski, J. J., Westneat, M., Diaz De Astarloa, J. M., Williams, J. T., Santos, M. D., Domínguez-Domínguez, O., Ortí, G., Arcila, D., & Betancur-R, R. (2024). Phylogenomic and comparative genomic analyses support a single evolutionary origin of flatfish asymmetry. Nature Genetics. https://doi.org/10.1038/s41588-024-01784-w
Egan, J. P., Simons, A. M., Alavi-Yeganeh, M. S., Hammer, M. P., Tongnunui, P., Arcila, D., Betancur-R, R., & Bloom, D. D. (2024). Phylogenomics, Lineage Diversification Rates, and the Evolution of Diadromy in Clupeiformes (Anchovies, Herrings, Sardines, and Relatives). Systematic Biology, syae022. https://doi.org/10.1093/sysbio/syae022
Mihalič, F., Arcila, D., Pettersson, M. E., Farkhondehkish, P., Andersson, E., Andersson, L., Betancur-R, R., & Jemth, P. (2024). Conservation of affinity rather than sequence underlies a dynamic evolution of the motif-mediated p53/MDM2 interaction in ray-finned fishes. Molecular Biology and Evolution, msae018. https://doi.org/10.1093/molbev/msae018
Drabeck, D. H., Wiese, J., Gilbertson, E., Arroyave, J., Stiassny, M. L. J., Alter, S. E., Borowsky, R., Hendrickson, D. A., Arcila, D., & McGaugh, S. E. (2024). Gene loss and relaxed selection of plaat1 in vertebrates adapted to low-light environments. Proceedings of the Royal Society B: Biological Sciences, 291(2024), 20232847. https://doi.org/10.1098/rspb.2023.2847
Heiple, Z., Huie, J. M., Medeiros, A. P. M., Hart, P. B., Goatley, C. H. R., Arcila, D., & Miller, E. C. (2023). Many ways to build an angler: diversity of feeding morphologies in a deep-sea evolutionary radiation. Biology Letters, 19(6). https://doi.org/ARTN 20230049 10.1098/rsbl.2023.0049
Arcila, D., Rincon-Sandoval, M., Hanson, W., Hart, P. B., González, V. L., Betancur-R, R., & Bichuette, M. E. (2023). Transcriptomic analysis of the Brazilian blind characid, Stygichthys typhlops, reveals convergent selection with Astyanax mexicanus and other cavefishes. Frontiers in Ecology and Evolution, 11, 1076756. https://doi.org/10.3389/fevo.2023.1076756
Baldwin, C. C., Arcila, D., Robertson, D. R., & Tornabene, L. (2023). Description of the First Species of Polylepion (Teleostei: Labridae) from the Atlantic Ocean with Analysis of Evolutionary Relationships of the New Species. Ichthyology & Herpetology, 111(2). https://doi.org/10.1643/i2022075
Collins, Q. P., Grunsted, M. J., Arcila, D., Xiong, Y., & Barmchi, M. P. (2023). Transcriptomic analysis provides insight into the mechanism of IKKβ-mediated suppression of HPV18E6-induced cellular abnormalities. G3-Genes Genomes Genetics, 13(4). https://doi.org/10.1093/g3journal/jkad020
Peterson, R. D., Sullivan, J. P., Hopkins, C. D., Santaquiteria, A., Dillman, C. B., Pirro, S., Betancur-R, R., Arcila, D., Hughes, L. C., & Ortí, G. (2022). Phylogenomics of Bony-Tongue Fishes (Osteoglossomorpha) Shed Light on the Craniofacial Evolution and Biogeography of the Weakly Electric Clade (Mormyridae). Systematic Biology, 71(5), 1032–1044. https://doi.org/10.1093/sysbio/syac001
Troyer, E. M., Betancur-R, R., Hughes, L. C., Westneat, M., Carnevale, G., White, W. T., Pogonoski, J. J., Tyler, J. C., Baldwin, C. C., Ortí, G., Brinkworth, A., Clavel, J., & Arcila, D. (2022). The impact of paleoclimatic changes on body size evolution in marine fishes. Proceedings of the National Academy of Sciences of the United States of America, 119(29). https://doi.org/ARTN e2122486119 10.1073/pnas.2122486119
Briñoccoli, Y. F., Bogan, S., Arcila, D., Rosso, J. J., Mabragaña, E., Delpiani, S. M., de Astarloa, J. M. D., & Cardoso, Y. P. (2022). Molecular and morphological evidence revalidates Acrobrycon tarijae (Characiformes, Characidae) and shows hidden diversity. Zookeys, 1091, 99–117. https://doi.org/10.3897/zookeys.1091.73446
Arcila, D., & Orti, G. (2022). Phylogenetic Systematics of Fishes. In S. Midway, C. Hasler, & P. Chakrabarty (Eds.), Methods for Fish Biology, 2nd edition (2nd ed.). American Fisheries Society.
Santaquiteria, A., Siqueira, A. C., Duarte-Ribeiro, E., Carnevale, G., White, W. T., Pogonoski, J. J., Baldwin, C. C., Ortí, G., Arcila, D., & Betancur-R, R. (2021). Phylogenomics and Historical Biogeography of Seahorses, Dragonets, Goatfishes, and Allies (Teleostei: Syngnatharia): Assessing Factors Driving Uncertainty in Biogeographic Inferences. Systematic Biology, 70(6), 1145–1162. https://doi.org/10.1093/sysbio/syab028
Arcila, D., Hughes, L. C., Meléndez-Vazquez, B., Baldwin, C. C., White, W. T., Carpenter, K. E., Williams, J. T., Santos, M. D., Pogonoski, J. J., Miya, M., Ortí, G., & Betancur-R, R. (2021). Testing the Utility of Alternative Metrics of Branch Support to Address the Ancient Evolutionary Radiation of Tunas, Stromateoids, and Allies (Teleostei: Pelagiaria). Systematic Biology, 70(6), 1123–1144. https://doi.org/10.1093/sysbio/syab018
Atta, C. J., Yuan, H., Li, C. H., Arcila, D., Betancur-R, R., Hughes, L. C., Ortí, G., & Tornabene, L. (2021). Exon-capture data and locus screening provide new insights into the phylogeny of flatfishes (Pleuronectoidei). Molecular Phylogenetics and Evolution, 166. https://doi.org/https://doi.org/10.1016/j.ympev.2021.107315
Rincon-Sandoval, M., Duarte-Ribeiro, E., Davis, A. M., Santaquiteria, A., Hughes, L. C., Baldwin, C. C., Soto-Torres, L., Acero, A., Walker, H. J., Carpenter, K. E., Sheaves, M., Orti, G., Arcila, D., & Betancur-R, R. (2020). Evolutionary determinism and convergence associated with water-column transitions in marine fishes. Proceedings of the National Academy of Sciences of the United States of America, 117(52), 33396–33403. https://doi.org/10.1073/pnas.2006511117
Hughes, L. C., Ortí, G., Saad, H., Li, C. H., White, W. T., Baldwin, C. C., Crandall, K. A., Arcila, D., & Betancur, R. (2020). Exon probe sets and bioinformatics pipelines for all levels of fish phylogenomics. Mol Ecol Resour, 21(3), 816–833. https://doi.org/10.1111/1755-0998.13287
Kolmann, M. A., Hughes, L. C., Hernandez, L. P., Arcila, D., Betancur-R, R., Sabaj, M. H., López-Fernández, H., & Ortí, G. (2020). Phylogenomics of Piranhas and Pacus (Serrasalmidae) Uncovers How Dietary Convergence and Parallelism Obfuscate Traditional Morphological Taxonomy. Systematic Biology, 70(3), 576–592. https://doi.org/10.1093/sysbio/syaa065
Meléndez-Vazquez, F., Olmeda-Saldaña, M., Cruz, J., Arcila, D., & Betancur, R. (2019). Effects of Hurricane Maria in hamlet communities (Serranidae: spp.) in Puerto Rico. Ecological Indicators, 107. https://doi.org/ARTN 105591 10.1016/j.ecolind.2019.105591
Bemis, K. E., Tyler, J. C., & Arcila, D. (2019). Life history, distribution and molecular phylogenetics of the Upward-Mouth Spikefish Atrophacanthus japonicus (Teleostei: Tetraodontiformes: Triacanthodidae). Journal of Fish Biology, 94(4), 578–584. https://doi.org/10.1111/jfb.13923
Betancur-R, R., Arcila, D., Vari, R. P., Hughes, L. C., Oliveira, C., Sabaj, M. H., & Ortí, G. (2019). Phylogenomic incongruence, hypothesis testing, and taxonomic sampling: The monophyly of characiform fishes. Evolution, 73(2), 329–345. https://doi.org/10.1111/evo.13649
Hughes, L. C., Ortí, G., Huang, Y., Sun, Y., Baldwin, C. C., Thompson, A. W., Arcila, D., Betancur, R. R., Li, C., Becker, L., Bellora, N., Zhao, X., Li, X., Wang, M., Fang, C., Xie, B., Zhou, Z., Huang, H., Chen, S., … Shi, Q. (2018). Comprehensive phylogeny of ray-finned fishes (Actinopterygii) based on transcriptomic and genomic data. Proc Natl Acad Sci U S A, 115(24), 6249–6254. https://doi.org/10.1073/pnas.1719358115
Arcila, D., Petry, P., & Ortí, G. (2018). Phylogenetic relationships of the family Tarumaniidae (Characiformes) based on nuclear and mitochondrial data. Neotropical Ichthyology, 16(3). https://doi.org/Artn 180016 10.1590/1982-0224-20180016
Arcila, D., & Tyler, J. C. (2017). Mass extinction in tetraodontiform fishes linked to the Palaeocene-Eocene thermal maximum. Proceedings of the Royal Society B-Biological Sciences, 284(1866). https://doi.org/ARTN 20171771 10.1098/rspb.2017.1771
Lavoué, S., Arnegard, M. E., Rabosky, D. L., McIntyre, P. B., Arcila, D., Vari, R. P., & Nishida, M. (2017). Trophic evolution in African citharinoid fishes (Teleostei: Characiformes) and the origin of intraordinal pterygophagy. Molecular Phylogenetics and Evolution, 113, 23–32. https://doi.org/https://doi.org/10.1016/j.ympev.2017.05.001
Arcila, D., Orti, G., Vari, R., Armbruster, J. W., Stiassny, M. L. J., Ko, K. D., Sabaj, M. H., Lundberg, J., Revell, L. J., & Betancur, R. (2017). Genome-wide interrogation advances resolution of recalcitrant groups in the tree of life. Nature Ecology & Evolution, 1(2). https://doi.org/ARTN 0020 10.1038/s41559-016-0020
Bannikov, A. F., Tyler, J. C., Arcila, D., & Carnevale, G. (2017). A new family of gymnodont fish (Tetraodontiformes) from the earliest Eocene of the Peri-Tethys (Kabardino-Balkaria, northern Caucasus, Russia). Journal of Systematic Palaeontology, 15(2), 129–146. https://doi.org/10.1080/14772019.2016.1149115
Thomaz, A. T., Arcila, D., Ortí, G., & Malabarba, L. R. (2015). Molecular phylogeny of the subfamily Stevardiinae Gill, 1858 (Characiformes: Characidae): classification and the evolution of reproductive traits. Bmc Evolutionary Biology, 15. https://doi.org/ARTN 146 10.1186/s12862-015-0403-4
Arcila, D., Pyron, R. A., Tyler, J. C., Ortí, G., & Betancur-R, R. (2015). An evaluation of fossil tip-dating versus node-age calibrations in tetraodontiform fishes (Teleostei: Percomorphaceae). Molecular Phylogenetics and Evolution, 82, 131–145. https://doi.org/10.1016/j.ympev.2014.10.011
Arcila, D., Vari, R. P., & Menezes, N. A. (2013). Revision of the Neotropical Genus (Ostariophysi: Characiformes: Characidae) with Description of Two New Species. Copeia, 4, 604–611. https://doi.org/10.1643/Ci-13-009
Betancur-R, R., Broughton, R. E., Wiley, E. O., Carpenter, K., López, J. A., Li, C. H., Holcroft, N. I., Arcila, D., Sanciangco, M., Cureton, J. C., Zhang, F. F., Buser, T., Campbell, M. A., Ballesteros, J. A., Roa-Varon, A., Willis, S., Borden, W. C., Rowley, T., Reneau, P. C., … Ortí, G. (2013). The Tree of Life and a New Classification of Bony Fishes. Plos Currents-Tree of Life. https://doi.org/10.1371/currents.tol.53ba26640df0ccaee75bb165c8c26288
Rom√°n-Valencia, C., & Arcila-Mesa, D. K. (2010). Five new species of Hemibrycon (Characiformes: Characidae) from the Rio Magdalena basin, Colombia. Revista de BiologÌa Tropical, 58, 339+.
Román- Valencia, C., & Arcila, D. (2009). Two new species of Hemibrycon (Characiformes, Characidae) from the Magdalena River, Colombia. Animal Biodiversity and Conservation, 32. https://doi.org/10.32800/abc.2009.32.0077
Román-Valencia, C., Arcila-Mesa, D. K., & Hurtado T, H. (2009). Variación morfológica de los peces Hemibrycon boquiae y Hemibrycon rafaelense (Characiformes: Characidae) en el Río Cauca, Colombia. Revista de BiologÌa Tropical, 57(3), 541–556.
Román- Valencia, C., & Arcila, D. (2008). Hemibrycon rafaelense n. sp. (Characiformes, Characidae), a new species from the upper Cauca River, with keys to Colombian species. Animal Biodiversity and Conservation, 31. https://doi.org/10.32800/abc.2008.31.0067